ArticleCancer cell2010
HIF-1alpha partners with FoxA2, a neuroendocrine-specific transcription factor, to promote tumorigenesis.
Article in Cancer cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Alterations in AR-FOXA1 signaling in prostate cancer progression and therapeutic resistance.Journal of the National Cancer Center · 2026Review
- Roles and therapeutic potential of the SLC family in prostate cancer-literature review.BMC urology · 2025Review
- Article
- FOXA1 and FOXA2: the regulatory mechanisms and therapeutic implications in cancer.Cell death discovery · 2024Review
- Transcription Factors: The Fulcrum Between Cell Development and Carcinogenesis.Frontiers in oncology · 2021Review
- Effects of PropofolFrontiers in oncology · 2021Review
- Neuroendocrine Differentiation of Prostate Cancer-An Intriguing Example of Tumor Evolution at Play.Cancers · 2019Review
- Prostate cancer cell malignancy via modulation of HIF-1α pathway with isoflurane and propofol alone and in combination.British journal of cancer · 2014Article
- RANK-mediated signaling network and cancer metastasis.Cancer metastasis reviews · 2014Review
- A TRIP230-retinoblastoma protein complex regulates hypoxia-inducible factor-1α-mediated transcription and cancer cell invasion.PloS one · 2014Article
- HIF-1α induced by β-elemene protects human osteosarcoma cells from undergoing apoptosis.Journal of cancer research and clinical oncology · 2012Article
- Lineage plasticity-mediated therapy resistance in prostate cancer.Asian journal of andrologyReview
- Current advances of targeting epigenetic modifications in neuroendocrine prostate cancer.Tzu chi medical journalReview
Corrections and comments
- Comment on
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
In this issue of Cancer Cell, Qi et al. report a novel mechanism by which HIF-1alpha synergizes with a tissue-specific transcription factor, FoxA2, to promote a transcriptional program that supports prostate tumor formation and progression.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.