Evidence map›Paper›PMID 20607151›Full record

ArticleLab on a chip2010

Laboratory-scale protein striping system for patterning biomolecules onto paper-based immunochromatographic test strips.

Michael A Nash, John M Hoffman, Dean Y Stevens, Allan S Hoffman, Patrick S Stayton, Paul Yager

Abstract read
In one paragraph

Article in Lab on a chip, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michael A NashUniversity of Washington, Department of Bioengineering, Box 355061, 3720 15th Ave NE, Seattle, WA 98195-5061, USA. mikenash@uw.edu
John M Hoffman
Dean Y Stevens
Allan S Hoffman
Patrick S Stayton
Paul Yager
University of Washington · US

Funding

Smart ConjugatesR01EB000252 · NIBIB · UNIVERSITY OF WASHINGTON · PI STAYTON, PATRICK S. · 2002 to 2011
$3.5M
NIBIB NIH HHS EB000252NIBIB NIH HHS R01 EB000252
6 · The paper itself

Abstract

A method for patterning narrow lines of biomolecules onto nitrocellulose membranes using laboratory syringe pumps is described. One syringe pump is used to drive the biomolecule solution through a needle, while another modified syringe pump acts as a one-dimensional translation stage, moving the needle across the membrane much like a pen. This method consumes very small volumes of reagents, and is a viable option for laboratory-scale fabrication and prototyping of point-of-care rapid diagnostic test strips.

Indexed as

PaperReagent StripsAnimalsAntibodies, ImmobilizedBiosensing TechniquesClinical Laboratory TechniquesEquipment DesignGoldHumansImmunoassayImmunoglobulin GMetal NanoparticlesProteinsStreptavidinSyringesTime FactorsAntibodies, ImmobilizedGoldImmunoglobulin GProteinsReagent StripsStreptavidin

Identifiers

PMID20607151
PMCPMC3100345
OpenAlexW2136040710

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.