ArticleJournal of global infectious diseases2010
In vitro antibacterial activity of Ibuprofen and acetaminophen.
Article in Journal of global infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 79 citations in OpenAlex.
- Antimicrobial potentials and challenges of paracetamol: A comprehensive reassessment based on database reports.Pharmaceutical science advances · 2025Review
- New Frontiers for Old Medications: Repurposing Approved Drugs Against Gram-Negative Bacterial Infections.Microorganisms · 2025Review
- Removal of Ibuprofen from Contaminated Water by Bioaugmentation with Novel Bacterial Strains Isolated from Sewage Sludge.Microorganisms · 2025Article
- Novel Buccal Xanthan Gum-Hyaluronic Acid Eutectogels with Dual Anti-Inflammatory and Antimicrobial Properties.Gels (Basel, Switzerland) · 2025Article
- Anti-inflammatory drugs as potential antimicrobial agents: a review.Frontiers in pharmacology · 2025Review
- Repurposing of dibucaine and niflumic acid as antimicrobial agents in combination with antibiotics against Staphylococcus aureus.The Journal of antibiotics · 2024Article
- Article
- Proven anti-virulence therapies in combating methicillin- and vancomycin-resistantFrontiers in cellular and infection microbiology · 2024Article
- Composite Hydrogels with Embedded Silver Nanoparticles and Ibuprofen as Wound Dressing.Gels (Basel, Switzerland) · 2023Article
- Biological Activity and Thrombogenic Properties of Oxide Nanotubes on the Ti-13Nb-13Zr Biomedical Alloy.Journal of functional biomaterials · 2023Article
- Review
- Physicochemical and Bioactivity Characteristics of Doxycycline Hyclate-Loaded Solvent Removal-Induced Ibuprofen-Based In Situ Forming Gel.Gels (Basel, Switzerland) · 2023Article
- Enhancing Dissolution Rate and Antibacterial Efficiency of Azithromycin through Drug-Drug Cocrystals with Paracetamol.Antibiotics (Basel, Switzerland) · 2021Article
- Roles of Eicosanoids in Regulating Inflammation and Neutrophil Migration as an Innate Host Response to Bacterial Infections.Infection and immunity · 2021Article
- Nonsteroidal antiinflammatory drugs alter antibiotic susceptibility and expression of virulence-related genes and protein A of Staphylococcus aureusTurkish journal of medical sciences · 2021Article
- Synergistic Effects of Propolis Combined with 2-Phenoxyethanol and Antipyretics on the Growth ofPharmaceutics · 2021Article
- Metformin as a Potential Adjuvant Antimicrobial Agent Against Multidrug Resistant Bacteria.Clinical pharmacology : advances and applications · 2021Article
- Optimal Design of THEDES Based on Perillyl Alcohol and Ibuprofen.Pharmaceutics · 2020Article
- Nanomagnetite-embedded PLGA Spheres for Multipurpose Medical Applications.Materials (Basel, Switzerland) · 2019Article
- Abiotic degradation and environmental toxicity of ibuprofen: Roles of mineral particles and solar radiation.Water research · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIbuprofen and acetaminophen are common chemical agents that have anti-inflammatory, antipyretic, and analgesic activity.
aimsTo detect any potential antibacterial effects of ibuprofen and acetaminophen on pathogenic bacteria. MATERIALS AND
methodsIbuprofen and acetaminophen were tested for antibacterial activity against seven isolates of bacteria including gram positive bacteria (Staphylococci aureus and Bacillus subtilis) and gram negative bacteria (E. coli, Enterobacter aerogenes, Enterobacter cloacae, Salmonella typhi and Paracoccus yeei). Spectrophotometer assay was applied to determine the antibacterial activities of ibuprofen and acetaminophen. Three controls were included in this study: Ampicilline sodium (20 mug/ml); cefotaxime sodium (20 mug/ml) and chemical free medium.
resultsStaphylococcus aureus and Paracoccus yeei were susceptible to lower concentrations of ibuprofen and acetaminophen (MIC=1.25 mg/ml), while two strains of Enterobacter exhibited resistance to these agents.
conclusionsIbuprofen and acetaminophen showed a potential antibacterial effect on isolated strains of bacteria. They had the same ability to inhibit bacterial growth.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.