ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2010
Invertebrate central pattern generator circuits.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
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Who cites it
70 citing papers in PubMed.
- Neural connectome of the ctenophore statocyst.eLife · 2026Article
- Dynamic emotion fabric theory: a new framework for understanding the biology of flexible emotion states.Social cognitive and affective neuroscience · 2026Review
- Diffuse pacemaker mechanism with distinctive organization drives pulsation in the octocoralProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Dynamics of neural activity in early nervous system evolution.Current opinion in behavioral sciences · 2024Article
- Interdependence of cellular and network properties in respiratory rhythmogenesis.bioRxiv : the preprint server for biology · 2023Article
- Linking neural circuits to the mechanics of animal behavior inFrontiers in neural circuits · 2023Review
- Editorial: Invertebrate neurophysiology-of currents, cells, and circuits.Frontiers in neuroscience · 2023Article
- Regulation of excitation-contraction coupling at the Drosophila neuromuscular junction.The Journal of physiology · 2022Article
- Neurobiological reduction: From cellular explanations of behavior to interventions.Frontiers in psychology · 2022Review
- Article
- Extracting temporal relationships between weakly coupled peptidergic and motoneuronal signaling: Application to Drosophila ecdysis behavior.PLoS computational biology · 2021Article
- Lesions of abdominal connectives reveal a conserved organization of the calling song central pattern generator (CPG) network in different cricket species.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2021Article
- Article
- Transcriptional profiling of identified neurons in leech.BMC genomics · 2021Article
- Review
- Effects of calcium-activated potassium channel modulators on afterhyperpolarizing potentials in identified motor and mechanosensory neurons of the medicinal leech.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2021Article
- Modular timer networks: abdominal interneurons controlling the chirp and pulse pattern in a cricket calling song.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2020Article
- On the Role of the Head Ganglia in Posture and Walking in Insects.Frontiers in physiology · 2020Review
- Feedforward discharges couple the singing central pattern generator and ventilation central pattern generator in the cricket abdominal central nervous system.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2019Article
- Robust dynamical invariants in sequential neural activity.Scientific reports · 2019Article
10 more citing papers are in PubMed but not listed here.
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1 author.
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Abstract
There are now a reasonable number of invertebrate central pattern generator (CPG) circuits described in sufficient detail that a mechanistic explanation of how they work is possible. These small circuits represent the best-understood neural circuits with which to investigate how cell-to-cell synaptic connections and individual channel conductances combine to generate rhythmic and patterned output. In this review, some of the main lessons that have appeared from this analysis are discussed and concrete examples of circuits ranging from single phase to multiple phase patterns are described. While it is clear that the cellular components of any CPG are basically the same, the topology of the circuits have evolved independently to meet the particular motor requirements of each individual organism and only a few general principles of circuit operation have emerged. The principal usefulness of small systems in relation to the brain is to demonstrate in detail how cellular infrastructure can be used to generate rhythmicity and form specialized patterns in a way that may suggest how similar processes might occur in more complex systems. But some of the problems and challenges associated with applying data from invertebrate preparations to the brain are also discussed. Finally, I discuss why it is useful to have well-defined circuits with which to examine various computational models that can be validated experimentally and possibly applied to brain circuits when the details of such circuits become available.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.