ArticlePain practice : the official journal of World Institute of Pain
Differences in comorbidities on low back pain and low back related leg pain.
Article in Pain practice : the official journal of World Institute of Pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Longitudinal variations of paraspinal muscle fatty infiltration in obese patients after bariatric surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Radiofrequency Ablation for Chronic Pain: Mechanistic Insights and Emerging Innovations.Cureus · 2025Review
- Patient self-reported musculoskeletal symptoms before and after the interruption of chiropractic care during the COVID-19 lockdown in Ontario, Canada: a retrospective case series.The Journal of the Canadian Chiropractic Association · 2025Article
- Nightmare disorder and low back pain in veterans: cross-sectional association and effect over time.Sleep advances : a journal of the Sleep Research Society · 2022Article
- Advances in research on fat infiltration and lumbar intervertebral disc degeneration.Frontiers in endocrinology · 2022Review
- Predictors of pain and disability outcomes in one thousand, one hundred and eight patients who underwent lumbar discectomy surgery.International orthopaedics · 2015Article
- Older Age and Leg Pain Are Good Predictors of Pain and Disability Outcomes in 2710 Patients Who Receive Lumbar Fusion.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2015Article
- Differential diagnosis of shoulder and cervical pain: a case report.The Journal of manual & manipulative therapy · 2010Article
- Pulsed electromagnetic field therapy effectiveness in low back pain: A systematic review of randomized controlled trials.Porto biomedical journalReview
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveInvestigate the influence of external factors such as depression and BMI among subjects with primary severe low back pain (LBP) and low back related leg pain (LBLP).
backgroundThe report of disability in patients with LBP may be significantly influenced by confounding and moderating variables. No similar studies have examined the influence of these factors on LBLP.
methodsThis study included 1,448 consecutive subjects referred to a tertiary spine clinic. Unconditional binary logistic regression was used to determine the influence of comorbidities on the relationship between self-reported back and leg pain. A change in estimate formula was used to quantify this relationship.
resultsAmong those subjects with primary LBP the unadjusted odds ratio was 8.58 (95% CI 4.87, 15.10) and when adjusting for BMI, depression and smoking was 5.94 (95% CI 3.04, 11.60) resulting in a 36.7% change due to confounding by these comorbidities. Among those with primary LBLP, the unadjusted odds ratio was 4.49 (95% CI 2.78, 7.27) and when adjusting for BMI and depression was 4.60 (95% CI 2.58, 8.19) resulting in a 1.7% change due to confounding by these comorbidities.
conclusionThe disability statuses of the patients with primary LBP in this study were more significantly affected by comorbidities of BMI, depression and smoking than patients with report of LBLP. However, these comorbidities contribute little to the relationship of primary low back related leg pain and Oswestry scores ≥ 40.
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