Trial reportAIDS (London, England)2010
Reducing HIV risk behavior of men who have sex with men through persuasive computing: results of the Men's INTernet Study-II.
Trial report in AIDS (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- eHealth Interventions to Address HIV and Other Sexually Transmitted Infections, Sexual Risk Behavior, Substance Use, and Mental Ill-health in Men Who Have Sex With Men: Systematic Review and Meta-analysis.JMIR public health and surveillance · 2022Pooled it
- What is the added value of incorporating pleasure in sexual health interventions? A systematic review and meta-analysis.PloS one · 2022Pooled it
- Behavioural interventions delivered through interactive social media for health behaviour change, health outcomes, and health equity in the adult population.The Cochrane database of systematic reviews · 2021Pooled it
- eHealth Interventions to Address Sexual Health, Substance Use, and Mental Health Among Men Who Have Sex With Men: Systematic Review and Synthesis of Process Evaluations.Journal of medical Internet research · 2021Pooled it
- Theories of change for e-health interventions targeting HIV/STIs and sexual risk, substance use and mental ill health amongst men who have sex with men: systematic review and synthesis.Systematic reviews · 2021Pooled it
- The Effectiveness of Electronic Health Interventions for Promoting HIV-Preventive Behaviors Among Men Who Have Sex With Men: Meta-Analysis Based on an Integrative Framework of Design and Implementation Features.Journal of medical Internet research · 2020Pooled it
- A Systematic Review of eHealth Interventions Addressing HIV/STI Prevention Among Men Who Have Sex With Men.AIDS and behavior · 2019Pooled it
- eHealth interventions for HIV prevention in high-risk men who have sex with men: a systematic review.Journal of medical Internet research · 2014Pooled it
- A systematic review to identify challenges of demonstrating efficacy of HIV behavioral interventions for gay, bisexual, and other men who have sex with men (MSM).AIDS and behavior · 2013Pooled it
- Internet-based randomized controlled trials: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2013Pooled it
- Online HIV prevention intervention on condomless sex among men who have sex with men: a web-based randomized controlled trial.BMC infectious diseases · 2019Trial
- A Randomized Trial to Evaluate the Efficacy of a Web-Based HIV Behavioral Intervention for High-Risk African American Women.AIDS and behavior · 2015Trial
- Reducing shame in a game that predicts HIV risk reduction for young adult MSM: a randomized trial delivered nationally over the Web.Journal of the International AIDS Society · 2013Trial
- Feasibility, acceptability, and preliminary efficacy of an online HIV prevention program for diverse young men who have sex with men: the keep it up! intervention.AIDS and behavior · 2013Trial
- Feasibility, acceptability and preliminary efficacy of an online peer-to-peer social support ART adherence intervention.AIDS and behavior · 2013Trial
- Strategies to retain participants in a long-term HIV prevention randomized controlled trial: lessons from the MINTS-II study.AIDS and behavior · 2012Trial
- An online randomized controlled trial evaluating HIV prevention digital media interventions for men who have sex with men.PloS one · 2012Trial
- Correlates of never testing for HIV among men who have sex with men in Nepal.PLOS global public health · 2025Article
- Ehealth interactive intervention in promoting safer sex among men who have sex with men.NPJ digital medicine · 2024Article
- Interventions, Barriers, and Facilitators to Address the Sexual Problems of Gay, Bisexual and Other Men Who Have Sex with Men Living with HIV: A Rapid Scoping Review.AIDS and behavior · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveThe primary objective of this study was to develop and test a highly interactive Internet-based HIV prevention intervention for men who have sex with men (MSM). MSM remain the group at highest risk for HIV/AIDS in the United States and similar countries. As the Internet becomes popular for seeking sex, online interventions to reduce sexual risk are critical. Given previous studies, a secondary objective was to demonstrate that good retention is possible in online trials.
designA randomized controlled trial with 3-month, 6-month, 9-month, and 12-month follow-up design was employed.
methodsIn 2008, 650 participants were randomized to an online, interactive sexual risk reduction intervention or to a waitlist null control.
resultsRetention was 76-89% over 12 months. At 3-month follow-up, results showed a 16% reduction in reported unprotected anal intercourse risk among those in the treatment condition versus control [95% confidence interval (95% CI) of rate ratio: 0.70-1.01]. No meaningful differences were observed at 12-month follow-up.
conclusionInternet-based, persuasive computing programs hold promise as an effective new approach to HIV prevention for MSM, at least in the short term. Further, online trials can be conducted with acceptable retention provided strong retention protocols are employed. Four directions for future research are identified.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.