Evidence map›Paper›PMID 20600960›Full record

ArticleNeuroImage2010

Waxholm space: an image-based reference for coordinating mouse brain research.

G Allan Johnson, Alexandra Badea, Jeffrey Brandenburg, Gary Cofer, Boma Fubara, Song Liu, Jonathan Nissanov

Abstract read
In one paragraph

Article in NeuroImage, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 168 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
168citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

168 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Article
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  9. Preclinical evaluation of [Journal of molecular medicine (Berlin, Germany) · 2025
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  16. Multiscale comparative connectomics.Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
  17. Article
  18. Preclinical evaluation of the novel [European journal of nuclear medicine and molecular imaging · 2024
    Article
  19. Article
  20. Article

108 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

G Allan JohnsonDuke Center for In Vivo Microscopy, Radiology, Duke University Medical Center, Durham, NC 27710, USA. gjohnson@duke.edu
Alexandra Badea
Jeffrey Brandenburg
Gary Cofer
Boma Fubara
Song Liu
Jonathan Nissanov

Funding

YALE CENTER FOR THE: LEARNING &ATTENTIONP41RR013642 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARER, ELAINE L · 1998 to 2011
$21.9M
X-RAY RESEARCH AND DEVELOPMENT WITH/WITHOUT LIVE ANIMALSP41RR005959 · NCRR · DUKE UNIVERSITY · PI DZAU, VICTOR J · 1990 to 2011
$16.0M
MOUSE BIRNU24RR021760 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TOGA, ARTHUR W · 2005 to 2009
$11.6M
Small Animal Imaging Resource ProgramU24CA092656 · NCI · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2007 to 2011
$2.2M
NCI NIH HHS U24 CA092656NCRR NIH HHS P41 RR005959NCRR NIH HHS P41 RR013642NCRR NIH HHS U24 RR021760
6 · The paper itself

Abstract

We describe an atlas of the C57BL/6 mouse brain based on MRI and conventional Nissl histology. Magnetic resonance microscopy was performed on a total of 14 specimens that were actively stained to enhance tissue contrast. Images were acquired with three different MR protocols yielding contrast dependent on spin lattice relaxation (T1), spin spin relaxation (T2), and magnetic susceptibility (T2*). Spatial resolution was 21.5 mum (isotropic). Conventional histology (Nissl) was performed on a limited set of these same specimens and the Nissl images were registered (3D-to-3D) to the MR data. Probabilistic atlases for 37 structures are provided, along with average atlases. The availability of three different MR protocols, the Nissl data, and the labels provides a rich set of options for registration of other atlases to the same coordinate system, thus facilitating data-sharing. All the data is available for download via the web.

Indexed as

AnimalsAtlases as TopicBrainDatabases, FactualHistologyImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiceMice, Inbred C57BLReference StandardsStaining and LabelingThalamus

Identifiers

PMID20600960
PMCPMC2930145

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.