ReviewSeminars in cancer biology2010
V(D)J recombination: Born to be wild.
Review in Seminars in cancer biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Chromosome organization affects genome evolution in Sulfolobus archaea.Nature microbiology · 2022Article
- Preserving genome integrity in human cells via DNA double-strand break repair.Molecular biology of the cell · 2020Review
- More than one antibody of individual B cells revealed by single-cell immune profiling.Cell discovery · 2019Article
- Diversity of Immunoglobulin (Ig) Isotypes and the Role of Activation-Induced Cytidine Deaminase (AID) in Fish.Molecular biotechnology · 2018Review
- The RAG transposon is active through the deuterostome evolution and domesticated in jawed vertebrates.Immunogenetics · 2017Article
- Useful parasites: the evolutionary biology and biotechnology applications of transposable elements.Journal of genetics · 2016Review
- Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Mechanisms for Structural Variation in the Human Genome.Current genetic medicine reports · 2013Article
- Elevated expression of artemis in human fibroblast cells is associated with cellular radiosensitivity and increased apoptosis.British journal of cancer · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Vertebrates employ V(D)J recombination to generate diversity for an adaptive immune response. Born of a transposon, V(D)J recombination could conceivably cause more trouble than its worth. However, of the two steps required for transposon mobility (excision and integration) this particular transposon's integration step appears mostly blocked in cells. The employment of a transposon as raw material to develop adaptive immunity was thus a less-risky choice than it might have been … but is it completely risk-free?
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.