Evidence map›Paper›PMID 20600585›Full record

ReviewMolecular and cellular endocrinology2011

Nuclear hormone receptors in parasitic helminths.

Wenjie Wu, Philip T LoVerde

Abstract readReview
In one paragraph

Review in Molecular and cellular endocrinology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Sex Difference in Amebiasis.Current topics in microbiology and immunology · 2023
    Article
  5. Molecular Cloning and Characterization of aPathogens (Basel, Switzerland) · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Nuclear hormone receptors in parasitic Platyhelminths.Molecular and biochemical parasitology · 2019
    Review
  10. Article
  11. Nuclear receptors: emerging drug targets for parasitic diseases.The Journal of clinical investigation · 2017
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wenjie WuDepartment of Biochemistry, School of Medicine and Biomedical Science, State University of New York, Buffalo, NY 14214, USA. w_wenjie@hotmail.com
Philip T LoVerde

Funding

SIGNAL TRANSDUCTION IN SCHISTOSOMESR01AI046762 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LOVERDE, PHILIP T · 2000 to 2004
$1.8M
NIAID NIH HHS AI46762NIAID NIH HHS R01 AI046762
6 · The paper itself

Abstract

Nuclear receptors (NRs) belong to a large protein superfamily that are important transcriptional modulators in metazoans. Parasitic helminths include parasitic worms from the Lophotrochozoa (Platyhelminths) and Ecdysozoa (Nematoda). NRs in parasitic helminths diverged into two different evolutionary lineages. NRs in parasitic Platyhelminths have orthologues in Deuterostomes, in arthropods or both with a feature of extensive gene loss and gene duplication within different gene groups. NRs in parasitic Nematoda follow the nematode evolutionary lineage with a feature of multiple duplication of SupNRs and gene loss.

Indexed as

PhylogenyAmino Acid SequenceAnimalsDNA-Binding ProteinsGene DeletionGene DuplicationMolecular Sequence DataNematodaPlatyhelminthsProtein Structure, TertiaryReceptors, Cytoplasmic and NuclearSequence HomologyDNA-Binding ProteinsReceptors, Cytoplasmic and Nuclear

Identifiers

PMID20600585
PMCPMC2974807

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.