ReviewExperimental parasitology2010
Molecular mechanisms of host cell invasion by Trypanosoma cruzi.
Review in Experimental parasitology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 45 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed.
- Endothelial transmigration by Trypanosoma cruzi.PloS one · 2013Trial
- Intracellular Parasitic Infections Caused byVaccines · 2025Review
- Influence of CK2 protein kinase activity on the interaction between Trypanosoma cruzi and its vertebrate and invertebrate hosts.Parasitology research · 2024Article
- A Review on the Immunological Response againstPathogens (Basel, Switzerland) · 2023Review
- Preclinical Studies and Drug Combination of Low-Cost Molecules for Chagas Disease.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Sheltered in Stromal Tissue Cells,Pathogens (Basel, Switzerland) · 2022Article
- The Kinetoplastid-Specific Protein TcCAL1 Plays Different Roles DuringFrontiers in cellular and infection microbiology · 2022Article
- Mechanisms Associated withLife (Basel, Switzerland) · 2021Review
- Galectins in Chagas Disease: A Missing Link BetweenFrontiers in microbiology · 2021Review
- Does Autoimmunity Play a Role in the Immunopathogenesis of Vasculitis Associated With Chronic Chagas Disease?Frontiers in cellular and infection microbiology · 2021Article
- Transcriptional Studies onFrontiers in cellular and infection microbiology · 2021Review
- 3-Dimensional organization and dynamics of the microsporidian polar tube invasion machinery.PLoS pathogens · 2020Article
- Induction of Effective Immunity against Trypanosoma cruzi.Infection and immunity · 2020Article
- Comparative Analysis of the Secretome and Interactome ofFrontiers in immunology · 2020Article
- Chagas Disease in the United States: a Public Health Approach.Clinical microbiology reviews · 2019Review
- Chagas Disease Serological Test Performance in U.S. Blood Donor Specimens.Journal of clinical microbiology · 2019Article
- Autophagic elimination of Trypanosoma cruzi in the presence of metals.Journal of microbiology (Seoul, Korea) · 2019Article
- Advances in understanding the role of adipose tissue and mitochondrial oxidative stress inF1000Research · 2019Review
- The marsupial trypanosome Trypanosoma copemani is not an obligate intracellular parasite, although it adversely affects cell health.Parasites & vectors · 2018Article
- Gene and Chromosomal Copy Number Variations as an Adaptive Mechanism Towards a Parasitic Lifestyle in Trypanosomatids.Current genomics · 2018Review
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
The protozoan parasite Trypanosoma cruzi, the etiologic agent of Chagas disease, is an obligate intracellular protozoan pathogen. Overlapping mechanisms ensure successful infection, yet the relationship between these cellular events and clinical disease remains obscure. This review explores the process of cell invasion from the perspective of cell surface interactions, intracellular signaling, modulation of the host cytoskeleton and endosomal compartment, and the intracellular innate immune response to infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.