ArticleJournal of insect physiology2010
Bioassays of compounds with potential juvenoid activity on Drosophila melanogaster: juvenile hormone III, bisepoxide juvenile hormone III and methyl farnesoates.
Article in Journal of insect physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 38 citations in OpenAlex.
- Juvenile Hormone Studies inFrontiers in physiology · 2021Review
- Quorum Sensing Activity and Hyphal Growth by External Stimuli in the Entomopathogenic FungusInsects · 2020Article
- Exquisite ligand stereoselectivity of aThe Journal of biological chemistry · 2019Article
- Juvenile hormone-activated phospholipase C pathway enhances transcriptional activation by the methoprene-tolerant protein.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Methyl farnesoate plays a dual role in regulating Drosophila metamorphosis.PLoS genetics · 2015Article
- Coordinated changes in JH biosynthesis and JH hemolymph titers in Aedes aegypti mosquitoes.Journal of insect physiology · 2015Article
- Juvenile Hormone Biosynthesis in Insects: What Is New, What Do We Know, and What Questions Remain?International scholarly research notices · 2014Review
- Precocious metamorphosis in the juvenile hormone-deficient mutant of the silkworm, Bombyx mori.PLoS genetics · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 4 countries.
Funding
Abstract
Metabolites of the 6,7,10,11 bisepoxide juvenile hormone III (JHB(3)), and other potential juvenoids, were tested for juvenile hormone activity using early instar or early stage pupae of Drosophila melanogaster. Importantly, methyl farnesoates were tested as they might have JH-like activity on Dipteran juveniles. Larvae were exposed to compounds in medium, or the compounds were applied to white puparia. In the assays employed in the present study, there was no indication for JH activity associated with the metabolites of JHB(3). The activity of methyl farnesoate (MF) was higher than that of JH III and far greater than bisepoxide JH III. As opposed to the two endogenous juvenile hormones, methyl farnesoate has weak activity in the white puparial bioassay. When fluorinated forms of methyl farnesoate, which is unlikely to be converted to JH, were applied to Drosophila medium to which fly eggs were introduced, there was a high degree of larval mortality, but no evidence of subsequent mortality at the pupal stage. One possible explanation for the results is that methyl farnesoate is active as a hormone in larval stages, but has little activity at the pupal stage where only juvenile hormone has a major effect.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.