Evidence map›Paper›PMID 20598938›Full record

ReviewCurrent opinion in microbiology2010

Manipulation of dendritic cell function by viruses.

Anthony L Cunningham, Heather Donaghy, Andrew N Harman, Min Kim, Stuart G Turville

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current opinion in microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 177 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. CD83 Regulates the Immune Responses in Inflammatory Disorders.International journal of molecular sciences · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Sjögren's Syndrome and Viral Infections.Rheumatology and therapy · 2021
    Review
  13. Article
  14. Review
  15. U7 snRNA: A tool for gene therapy.The journal of gene medicine · 2021
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Molecular therapy oncolytics · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anthony L CunninghamCentre for Virus Research, Westmead Millennium Institute, University of Sydney, Westmead, NSW 2145, Australia. tony_cunningham@wmi.usyd.edu.au
Heather Donaghy
Andrew N Harman
Min Kim
Stuart G Turville
University of Sydney · AUWestmead Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses manipulate the function of dendritic cells (DCs) to enhance their entry, spread, survival and transmission. This review summarises recently published work identifying how viruses alter the expression of receptors, antiviral molecules, disrupt signalling pathways, subvert trafficking pathways and even affect DC function via interactions with second or third cell types. Different viruses such as human immunodeficiency virus (HIV) and herpes viruses may have widely divergent and even opposite effects on DC function, determined by the need for transfer to a primary target cell, replication within the DC or various immunoevasive mechanisms.

Indexed as

AnimalsBiological TransportDendritic CellsHumansImmune EvasionImmunity, InnateReceptors, VirusSignal TransductionVirus DiseasesVirusesVirus InternalizationVirus ReplicationReceptors, Virus

Identifiers

PMID20598938
OpenAlexW2016772494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.