Evidence map›Paper›PMID 20597850›Full record

ArticleStatistical applications in genetics and molecular biology2010

Buckley-James boosting for survival analysis with high-dimensional biomarker data.

Zhu Wang, C Y Wang

Abstract read
In one paragraph

Article in Statistical applications in genetics and molecular biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  9. Empirical Likelihood for Censored Linear Regression and Variable Selection.Scandinavian journal of statistics, theory and applications · 2015
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zhu WangYale University, USA. zhu.wang@yale.edu
C Y Wang

Funding

Use of Biomarkers in Diagnosis, Prognosis, Risk Prediction and Early Detection ofP01CA053996 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HSU, LI · 1991 to 2015
$9.4M
Functional Methods for Radiation Exposure and Biomarker DataR01ES017030 · NIEHS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI WANG, CHING-YUN · 2010 to 2012
$944k
NCI NIH HHS CA53996NCI NIH HHS P01 CA053996NIEHS NIH HHS ES17030NIEHS NIH HHS R01 ES017030
6 · The paper itself

Abstract

There has been increasing interest in predicting patients' survival after therapy by investigating gene expression microarray data. In the regression and classification models with high-dimensional genomic data, boosting has been successfully applied to build accurate predictive models and conduct variable selection simultaneously. We propose the Buckley-James boosting for the semiparametric accelerated failure time models with right censored survival data, which can be used to predict survival of future patients using the high-dimensional genomic data. In the spirit of adaptive LASSO, twin boosting is also incorporated to fit more sparse models. The proposed methods have a unified approach to fit linear models, non-linear effects models with possible interactions. The methods can perform variable selection and parameter estimation simultaneously. The proposed methods are evaluated by simulations and applied to a recent microarray gene expression data set for patients with diffuse large B-cell lymphoma under the current gold standard therapy.

Indexed as

Models, StatisticalPredictive Value of TestsSurvival AnalysisBiomarkers, TumorGene Expression ProfilingHumansLymphoma, Large B-Cell, DiffuseOligonucleotide Array Sequence AnalysisBiomarkers, Tumor

Identifiers

PMID20597850
PMCPMC2904263

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.