Evidence map›Paper›PMID 20596866›Full record

GuidelineEuropean journal of nuclear medicine and molecular imaging2010

Procedure guidelines for PET/CT tumour imaging with 68Ga-DOTA-conjugated peptides: 68Ga-DOTA-TOC, 68Ga-DOTA-NOC, 68Ga-DOTA-TATE.

Irene Virgolini, Valentina Ambrosini, Jamshed B Bomanji, Richard P Baum, Stefano Fanti, Michael Gabriel, Nikolaos D Papathanasiou, Giovanna Pepe, Wim Oyen, Clemens De Cristoforo and 1 more

3 registry-linked trialsAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in European journal of nuclear medicine and molecular imaging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 176 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
176citing papers in PubMed, 4 pooled it
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01873248 early_phase1completednot on this mapstarted 2013, after this paper: background citation

Impact of 68Ga-DOTATATE PET/CT on the Management of Neuroendocrine Tumors: The Referring Physician's Perspective

TypeinterventionalSponsorJonsson Comprehensive Cancer CenterRan2013 to 2017Enrolled100ConditionsNeuroendocrine TumorsArms68Ga-DOTATATE
NCT02174679 no longer availablenot on this map

68Ga-DOTATATE Imaging in Neuroendocrine Tumors

Typeexpanded_accessSponsorJonsson Comprehensive Cancer CenterConditionsCarcinoid Cancer, Neuroendocrine Tumors, Medullary Thyroid Cancer, Cancers Expressing Somatostatin ReceptorsArms68Ga DOTATATE
NCT06611891 phase3recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of Somatostatin Receptor Expression in PET 68Ga-DOTATOC in Patients Followed for Metastatic Breast Cancer

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2025 to 2026Enrolled25ConditionsBreast Cancer MetastaticArms68Ga-DOTATOC
3 · Its place in the literature

Who cites it

176 citing papers in PubMed, 4 syntheses or guidelines pooled it, 443 citations in OpenAlex.

  1. Consensus document on the progression and treatment response criteria in gastroenteropancreatic neuroendocrine tumors.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2018
    Guideline
  2. Pooled it
  3. Guideline
  4. EANM 2012 guidelines for radionuclide imaging of phaeochromocytoma and paraganglioma.European journal of nuclear medicine and molecular imaging · 2012
    Guideline
  5. A Prospective, Randomized, Double-Blind Study to Evaluate the Safety, Biodistribution, and Dosimetry ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Trial
  6. Radioguided surgery with βScientific reports · 2020
    Trial
  7. Trial
  8. Influence of lanreotide on uptake ofEuropean journal of nuclear medicine and molecular imaging · 2019
    Trial
  9. Measured human dosimetry of 68Ga-DOTATATE.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2013
    Trial
  10. Peptide receptor radionuclide therapy with ¹⁷⁷Lu-DOTATATE: the IEO phase I-II study.European journal of nuclear medicine and molecular imaging · 2011
    Trial
  11. Coronary artery disease imaging with total-body PET.The British journal of radiology · 2026
    Review
  12. Review
  13. Normal organ [European journal of nuclear medicine and molecular imaging · 2026
    Article
  14. Article
  15. Review
  16. Review
  17. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  18. A Reassessment of the Clinical Utility ofJournal of surgical oncology · 2025
    Article
  19. Unveiling the potential of copper-61 vs. gallium-68 for SSTR PET imaging.European journal of nuclear medicine and molecular imaging · 2025
    Article
  20. Article

116 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 5 countries.

Irene VirgoliniMedical University of Innsbruck, Innsbruck, Austria.
Valentina Ambrosini
Jamshed B Bomanji
Richard P Baum
Stefano Fanti
Michael Gabriel
Nikolaos D Papathanasiou
Giovanna Pepe
Wim Oyen
Clemens De Cristoforo
Arturo Chiti
Universität Innsbruck · ATFondazione Humanitas per la Ricerca · ITPoliclinico S.Orsola-Malpighi · ITUniversity College London · GBRadboud University Medical Center · NLZentralklinik Bad Berka · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of these guidelines is to assist nuclear medicine physicians in recommending, performing, reporting and interpreting the results of somatostatin (SST) receptor PET/CT imaging using 68Ga-DOTA-conjugated peptides, analogues of octreotide, that bind to SST receptors. This imaging modality should not be regarded as the only approach to visualizing tumours expressing SST receptors or as excluding other imaging modalities useful for obtaining comparable results. The corresponding guidelines of 111In-pentetreotide scintigraphy imaging have been considered and partially integrated with this text. The same has been done with the relevant and recent literature in this field and the final result has been discussed by distinguished experts.

Indexed as

Gallium RadioisotopesHeterocyclic Compounds, 1-RingHumansImage Interpretation, Computer-AssistedInjectionsNeoplasmsOctreotidePositron-Emission TomographyQuality ControlResearch DesignTomography, X-Ray Computed1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidGallium RadioisotopesHeterocyclic Compounds, 1-RingOctreotide

Identifiers

PMID20596866
OpenAlexW2122196655

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.