ArticleInternational archives of occupational and environmental health2011
Biological monitoring for occupational acrylamide exposure from acrylamide production workers.
Article in International archives of occupational and environmental health, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Cigarette smoking is associated with acrylamide exposure among the U.S. population: NHANES 2011-2016.Environmental research · 2022Article
- Dietary Acrylamide Intake Alters Gut Microbiota in Mice and Increases Its Susceptibility toFoods (Basel, Switzerland) · 2021Article
- Harmonization of acronyms for volatile organic compound metabolites using a standardized naming system.International journal of hygiene and environmental health · 2021Article
- Brain-derived neurotrophic factor protects against acrylamide-induced neuronal and synaptic injury via the TrkB-MAPK-Erk1/2 pathway.Neural regeneration research · 2021Article
- Toxicity assessments of acrylamide in aquatic environment using two algae Nitzschia closterium and Scenedesmus quadricauda.Environmental science and pollution research international · 2020Article
- Feasibility of using urinary N7-(2-carbamoyl-2-hydroxyethyl) Guanine as a biomarker for acrylamide exposed workers.Journal of exposure science & environmental epidemiology · 2018Article
- Urinary biomarkers of smokers' exposure to tobacco smoke constituents in tobacco products assessment: a fit for purpose approach.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2013Article
- Simultaneous analysis of 28 urinary VOC metabolites using ultra high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (UPLC-ESI/MSMS).Analytica chimica acta · 2012Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe conducted a repeated-measurement study to (1) investigate the correlation between occupational exposure to airborne acrylamide (AA) and the time-dependent behavior of urinary AAMA, GAMA2, and GAMA3 and (2) calculate the estimated biological exposure index at the permissible exposure limit (PEL) level of 30 μg/m(3).
methodsForty-four workers were recruited--8 were AA-exposed and 36 were controls. Pre- and post-shift urine samples were collected from the exposed group in parallel with personal sampling for 8 consecutive days and only 1 day for the control group and analyzed using liquid chromatography-electrospray ionization/tandem mass spectrometry (LC-ESI-MS/MS).
resultsPost-shift urinary AAMA level was significantly associated with personal AA exposure (p < 0.001), indicating that urinary AAMA was a better AA exposure biomarker. The estimated urinary excretion of AAMA was 3.0 mg/g creatinine for nonsmoking workers exposed to the PEL of 30 μg/m(3). The median GAMA (the sum of GAMA2 and GAMA3)/AAMA ratio for exposed workers was 0.03 (range, 0.005-0.14), relatively lower than that of the nonoccupational group.
conclusionsAlthough sample size in this study was small, the repeated-measurement data provide useful reference for future studies related to biological monitoring of occupational exposure to AA.
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