ArticleHippokratia2010
Hypothyroidism - new aspects of an old disease.
Article in Hippokratia, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 44 citations in OpenAlex.
- Hypercholesterolemia induced by hypothyroidism is ameliorated by taurine supplementation through the hepatic AMPK/ACC pathway.Archives of endocrinology and metabolism · 2026Article
- Subtype-specific causal effects of hypothyroidism on obstructive sleep apnea: A bidirectional Mendelian randomization study.Medicine · 2025Article
- Hypothyroidism phenotypes, clinical characteristics, and factors associated with nodular thyroid disease in patients with hypothyroidism in Southern Ghana: a 6-year retrospective study.BMC endocrine disorders · 2025Article
- Article
- Is the acquired hypothyroidism a risk factor for developing psychiatric disorders?Frontiers in psychiatry · 2024Review
- Association between hypothyroidism and obstructive sleep apnea: a bidirectional Mendelian randomization study combined with the geo database.Frontiers in neurology · 2024Article
- Is beta-carotene consumption associated with thyroid hormone levels?Frontiers in endocrinology · 2023Review
- Causal relationship between particulate matter 2.5 and hypothyroidism: A two-sample Mendelian randomization study.Frontiers in public health · 2022Article
- Thyroid-optimized and thyroid-sparing radiotherapy in oral cavity and oropharyngeal carcinoma: A dosimetric study.Technical innovations & patient support in radiation oncology · 2021Article
- Selected Essential and Toxic Chemical Elements in Hypothyroidism-A Literature Review (2001-2021).International journal of molecular sciences · 2021Review
- The prevalence and clinical features associated of hypothyroidism among Thai systemic sclerosis patients.Scientific reports · 2021Article
- The Role of Illness-Related Beliefs in Depressive, Anxiety, and Anger Symptoms: An On-line Survey in Women With Hypothyroidism.Frontiers in psychiatry · 2021Article
- Improving the Quality of Life of Patients with an Underactive Thyroid Through mHealth: A Patient-Centered Approach.Women's health reports (New Rochelle, N.Y.) · 2021Article
- Review
- The effectiveness of cognitive- behavioral therapy on quality of life in women with hypothyroidism in the reproductive age: a randomized controlled trial.Thyroid research · 2020Article
- [Hand pain, muscle pain and swollen lips].Zeitschrift fur Rheumatologie · 2019Article
- Hypothyroidism as a Predictor of Surgical Outcomes in the Elderly.Frontiers in endocrinology · 2019Review
- No Association between 25 (OH) Vitamin D Level And Hypothyroidism among Females.Open access Macedonian journal of medical sciences · 2017Article
- Urinary and Milk Iodine Status in Neonates and Their Mothers during Congenital Hypothyroidism Screening Program in Eastern Azerbaijan: A Pilot Study.Iranian journal of public health · 2014Article
- The biochemical prognostic factors of subclinical hypothyroidism.Endocrinology and metabolism (Seoul, Korea) · 2014Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypothyroidism is divided in primary, caused by failure of thyroid function and secondary (central) due to the failure of adequate thyroid-stimulating hormone (TSH) secretion from the pituitary gland or thyrotrophin-releasing hormone (TRH) from the hypothalamus. Secondary hypothyroidism can be differentiated in pituitary and hypothalamic by the use of TRH test. In some cases, failure of hormone action in peripheral tissues can be recognized. Primary hypothyroidism may be clinical, where free T(4) (FT(4)) is decreased and TSH is increased or subclinical where FT(4) is normal and TSH is increased. In secondary hypothyroidism FT(4) is decreased and TSH is normal or decreased. Primary hypothyroidism is most commonly caused by chronic autoimmune thyroiditis, less common causes being radioiodine treatment and thyroidectomy. Salt iodination, which is performed routinely in many countries, may increase the incidence of overt hypothyroidism. The incidence of clinical hypothyroidism is 0.5-1.9% in women and <1% in men and of subclinical 3-13.6% in women and 0.7-5.7% in men. It is important to differentiate between clinical and subclinical hypothyroidism as in clinical symptoms are serious, even coma may occur, while in subclinical symptoms are less and may even be absent. Subclinical hypothyroidism may be transformed to clinical and as recent research has shown it may have various consequences, such as hyperlipidemia and increased risk for the development of cardiovascular disease, even heart failure, somatic and neuromuscular symptoms, reproductive and other consequences. The administration of novel tyrosine kinase inhibitors for the treatment of neoplastic diseases may induce hypothyroidism. Hypothyroidism is treated by the administration of thyroxine and the prognosis is excellent.
Indexed as
Identifiers
20596261PMC2895281W90303123What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.