Evidence map›Paper›PMID 20595915›Full record

ArticleJournal of occupational and environmental medicine2010

Mortality patterns among Paducah Gaseous Diffusion Plant workers.

Caroline Chan, Therese S Hughes, Susan Muldoon, Tim Aldrich, Carol Rice, Richard Hornung, Gail Brion, David J Tollerud

Abstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Radiotherapy for non-cancer diseases: benefits and long-term risks.International journal of radiation biology · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Mortality in a combined cohort of uranium enrichment workers.American journal of industrial medicine · 2017
    Article
  8. Article
  9. Article
  10. Occupational exposure to trichloroethylene and cancer risk for workers at the Paducah Gaseous Diffusion Plant.International journal of occupational medicine and environmental health · 2011
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Caroline ChanDepartment of Environmental and Occupational Health Sciences, School of Public Health and Information Sciences, University of Louisville, Louisville, KY 40202, USA. caroline.chan@louisville.edu
Therese S Hughes
Susan Muldoon
Tim Aldrich
Carol Rice
Richard Hornung
Gail Brion
David J Tollerud

Funding

UOFL ENVIRONMENTAL HEALTH SCIENCES TRAINING PROGRAMT32ES011564 · NIEHS · UNIVERSITY OF LOUISVILLE · PI David W Hein, John Pierce Wise · 2004 to 2026
$7.1M
Health Effects of Occupational Exposures in PGDP WorkersR01OH007650 · OH · UNIVERSITY OF LOUISVILLE · PI TOLLERUD, DAVID J · 2002 to 2007
$1.2M
NIEHS NIH HHS T32 ES011564NIOSH CDC HHS R01 OH007650NIOSH CDC HHS R01OH007650
6 · The paper itself

Abstract

objectiveTo determine whether Paducah Gaseous Diffusion Plant workers had mortality patterns that differed from the general US population and to investigate whether mortality patterns were associated with job title or workplace exposures.

methodsA retrospective occupational cohort mortality study was conducted on 6759 workers. Standardized mortality ratio analyses compared the cohort with the referent US population. Internal comparisons producing standardized rate ratios were conducted by job title, metal exposure, and cumulative internal and external radiation exposures.

resultsOverall mortality and cancer rates were lower than the referent population, reflecting a strong healthy worker effect. Individual not significant standardized mortality ratios and standardized rate ratios were noted for cancers of the lymphatic and hematopoietic tissue.

conclusionsAlthough relatively low exposures to radiation and metals did not produce statistically significant health effects, no significant elevations for lymphatic and hematopoietic cancers were consistent with previous studies of nuclear workers.

Indexed as

Occupational ExposureAdolescentAdultAgedCohort StudiesFemaleFluoridesHumansKentuckyMaleMiddle AgedNeoplasmsNuclear Power PlantsNuclear ReactorsOccupational DiseasesRetrospective StudiesFluoridesUranium Compoundsuranium hexafluoride

Identifiers

PMID20595915
PMCPMC2983475

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.