ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2010
Origin and propagation of human gastric slow-wave activity defined by high-resolution mapping.
Article in American journal of physiology. Gastrointestinal and liver physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 2 of them syntheses that pooled it.
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Who cites it
131 citing papers in PubMed, 2 syntheses or guidelines pooled it, 275 citations in OpenAlex.
- Systematic review of small intestine pacing parameters for modulation of gut function.Neurogastroenterology and motility · 2023Pooled it
- Abnormalities on Electrogastrography in Nausea and Vomiting Syndromes: A Systematic Review, Meta-Analysis, and Comparison to Other Gastric Disorders.Digestive diseases and sciences · 2022Pooled it
- The mechanism of transcutaneous gastric pacing treatment on gastrointestinal motility recovery and inflammation improvement in early-stage acute pancreatitis patients.BMC gastroenterology · 2024Trial
- Patterns of Abnormal Gastric Pacemaking After Sleeve Gastrectomy Defined by Laparoscopic High-Resolution Electrical Mapping.Obesity surgery · 2017Trial
- A Long Time Coming: How the Analysis of Gastric Slow-Wave Morphology May Improve the Diagnosis of Motility Disorders.Digestive diseases and sciences · 2026Article
- Gastroparesis Phenotyping: Current Methods and Emerging Opportunities With Magnetic Resonance Imaging.Neurogastroenterology and motility · 2026Review
- Gastric slow-wave morphology in health and disease.Digestive diseases and sciences · 2026Article
- Optical Mapping of Pacing-Elicited Slow Waves in the Swine Stomach: Role of Virtual Electrodes.Neurogastroenterology and motility · 2026Article
- Neural Gastric Electrical Stimulation: Future Prospects in Managing Gastric Emptying Disorders.Journal of neurogastroenterology and motility · 2026Review
- A compartmental model for simulating the gut-brain axis in gastric function regulation.Frontiers in physiology · 2026Article
- Gastric motility and its association with adiposity and metabolic health in a cohort of Sri Lankan office workers.World journal of gastrointestinal pathophysiology · 2025Article
- Implantable bioelectronics for gut electrophysiology.Nature communications · 2025Article
- Gastric Mixing and Acid Diffusion in a Human Stomach Simulated Using Smoothed Particle Hydrodynamics.Journal of food science · 2025Article
- Abnormal gastric electrophysiology following laparoscopic sleeve gastrectomy and associations with symptoms and quality of life.BJS open · 2025Article
- Detailed microCT imaging protocol for ex vivo rat stomachs with comparative analysis.Scientific reports · 2025Article
- Decoding Gastric Reflexes: The Role of Mechanosensitive Enteric Neurons in Stomach Motility.Neurogastroenterology and motility · 2025Review
- A Compartmental Model for Simulating the Gut-Brain Axis in Gastric Function Regulation.bioRxiv : the preprint server for biology · 2025Article
- Electromechanical coupling across the gastroduodenal junction.Acta physiologica (Oxford, England) · 2025Review
- Body surface gastric mapping facilitates the management of pediatric disorders of gut-brain interaction.Therapeutic advances in gastroenterology · 2025Review
- Assessment of Gastric Remnant Activity, Symptoms, and Quality of Life Following Gastric Bypass.Obesity surgery · 2024Article
71 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 1 institution in 4 countries.
Funding
Abstract
Slow waves coordinate gastric motility, and abnormal slow-wave activity is thought to contribute to motility disorders. The current understanding of normal human gastric slow-wave activity is based on extrapolation from data derived from sparse electrode recordings and is therefore potentially incomplete. This study employed high-resolution (HR) mapping to reevaluate human gastric slow-wave activity. HR mapping was performed in 12 patients with normal stomachs undergoing upper abdominal surgery, using flexible printed circuit board (PCB) arrays (interelectrode distance 7.6 mm). Up to six PCBs (192 electrodes; 93 cm(2)) were used simultaneously. Slow-wave activity was characterized by spatiotemporal mapping, and regional frequencies, amplitudes, and velocities were defined and compared. Slow-wave activity in the pacemaker region (mid to upper corpus, greater curvature) was of greater amplitude (mean 0.57 mV) and higher velocity (8.0 mm/s) than the corpus (0.25 mV, 3.0 mm/s) (P < 0.001) and displayed isotropic propagation. A marked transition to higher amplitude and velocity activity occurred in the antrum (0.52 mV, 5.9 mm/s) (P < 0.001). Multiple (3-4) wavefronts were found to propagate simultaneously in the organoaxial direction. Frequencies were consistent between regions (2.83 +/- 0.35 cycles per min). HR mapping has provided a more complete understanding of normal human gastric slow-wave activity. The pacemaker region is associated with high-amplitude, high-velocity activity, and multiple wavefronts propagate simultaneously. These data provide a baseline for future HR mapping studies in disease states and will inform noninvasive diagnostic strategies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.