Evidence map›Paper›PMID 20595488›Full record

ArticleThe American journal of tropical medicine and hygiene2010

Adrenal function status in patients with paracoccidioidomycosis after prolonged post-therapy follow-up.

Angela M Tobón, Carlos A Agudelo, Carlos A Restrepo, Carlos A Villa, William Quiceno, Santiago Estrada, Angela Restrepo

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. [Adrenalitis].Der Pathologe · 2016
    Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Angela M TobónMedical and Experimental Mycology Unit, Corporación para Investigaciones Biológicas, Medellín, Colombia.
Carlos A Agudelo
Carlos A Restrepo
Carlos A Villa
William Quiceno
Santiago Estrada
Angela Restrepo
Corporación para Investigaciones Biológicas · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study assessed adrenal function in patients with paracoccididioidomycosis who had been treated to determine a possible connection between high antibody titers and adrenal dysfunction attributable to persistence of the fungus in adrenal gland. Adrenal gland function was studied in 28 previously treated patients, 2 (7.1%) of whom were shown to have adrenal insufficiency and 7 (259%) who showed a below normal response to stimuli by adrenocorticotropic hormone. Paracoccidioides brasiliensis was detected in the adrenal gland from one of the patients with adrenal insufficiency. Although the study failed to demonstrate a significant difference between high antibody titers and low cortisol levels, the proportion of adrenal insufficiency detected and the subnormal response to adrenocorticotropic hormone confirmed that adrenal damage is an important sequela of paracoccidioidomycosis. Studies with a larger number of patients should be conducted to confirm the hypothesis of persistence of P. brasiliensis in adrenal gland after therapy.

Indexed as

Adrenal GlandsAdrenal InsufficiencyAlgorithmsDrug Therapy, CombinationFollow-Up StudiesHumansHydrocortisoneParacoccidioidesParacoccidioidomycosisHydrocortisone

Identifiers

PMID20595488
PMCPMC2912586
OpenAlexW1999527196

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.