ArticleThe American journal of psychiatry2010
The role of a prescription in anxiety medication use, abuse, and dependence.
Article in The American journal of psychiatry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- The epidemiology of benzodiazepine misuse: A systematic review.Drug and alcohol dependence · 2019Pooled it
- Patient experiences of benzodiazepine tapering: a qualitative study of treatment in addiction care.BMC psychiatry · 2026Article
- At-Home Telehealth-Supported Subcutaneous Ketamine Therapy for Safety, Feasibility, and Clinical Outcomes in Adults With Moderate to Severe Depression, Anxiety, or Posttraumatic Stress Disorder in a Large, Heterogeneous Cohort in the United States: Retrospective Cohort Study.Journal of medical Internet research · 2026Article
- Nationwide trends in diagnosed sedative, hypnotic or anxiolytic use disorders in adolescents and young adults enrolled in Medicaid: 2001-2019.Addiction (Abingdon, England) · 2025Article
- A prospective cohort of treatment-seeking patients with problematic use of prescription narcotic drugs: study protocol and baseline characteristics.BMC psychiatry · 2024Observational
- Assessment of beliefs and attitudes towards benzodiazepines using machine learning based on social media posts: an observational study.BMC psychiatry · 2024Observational
- Characteristics of patients with anxiety disorder without selective serotonin reuptake inhibitor prescription over a two-year period of pharmacotherapy.Neuropsychopharmacology reports · 2024Article
- Drug overdose risk with benzodiazepine treatment in young adults: Comparative analysis in privately and publicly insured individuals.Addiction (Abingdon, England) · 2024Article
- Pharmacological and Physiological Correlates of the Bidirectional Fear Phenotype of the Carioca Rats and Other Bidirectionally Selected Lines.Current neuropharmacology · 2023Review
- Benzodiazepine exposures among women of reproductive age in the US, 2004-2018.Human & experimental toxicology · 2021Article
- Association of New Perioperative Benzodiazepine Use With Persistent Benzodiazepine Use.JAMA network open · 2021Article
- Higher and Higher? Drug and Alcohol Use and Misuse among HIV-Vulnerable Men, Trans Men, and Trans Women Who Have Sex with Men in the United States.Substance use & misuse · 2021Article
- Age-specific risk of substance use disorders associated with controlled medication use and misuse subtypes in the United States.Addictive behaviors · 2019Article
- Does misuse lead to a disorder? The misuse of prescription tranquilizer and sedative medications and subsequent substance use disorders in a U.S. longitudinal sample.Addictive behaviors · 2018Article
- Opioid Analgesic Use in Patients with Ankylosing Spondylitis: An Analysis of the Prospective Study of Outcomes in an Ankylosing Spondylitis Cohort.The Journal of rheumatology · 2018Observational
- Medical and nonmedical use of prescription sedatives and anxiolytics: Adolescents' use and substance use disorder symptoms in adulthood.Addictive behaviors · 2017Article
- Prescription monitoring programs and emergency department visits involving benzodiazepine misuse: Early evidence from 11 United States metropolitan areas.The International journal on drug policy · 2016Article
- The National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) Waves 1 and 2: review and summary of findings.Social psychiatry and psychiatric epidemiology · 2015Review
- A prospective study of adolescents' nonmedical use of anxiolytic and sleep medication.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2015Article
- Treatment for illegal drug use disorders: the role of comorbid mood and anxiety disorders.BMC psychiatry · 2014Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectivePrescriptions for anxiety medications have increased substantially in recent years. Individuals with anxiety disorders are at risk of nonmedical use of these medications, but information about whether this risk is elevated among patients with a prescription for such medications is lacking. The authors compared risk of nonmedical use in individuals in a national sample with and without a prescription for anxiety medication and identified characteristics associated with nonmedical use.
methodData were drawn from face-to-face surveys of 34,653 adult participants in the National Epidemiologic Survey on Alcohol and Related Conditions. The risk of nonmedical use of prescription anxiety medication and associated drug use disorders was computed for individuals who had or had not ever received a prescription for anxiety medication; among those who had received a prescription, characteristics associated with nonmedical use were analyzed.
resultsPrescription of anxiety medication was associated with lifetime and past-year nonmedical use (odds ratios, 1.6 and 1.9, respectively) and lifetime DSM-IV abuse or dependence (odds ratio, 2.6). Among respondents who received a prescription (N=4,294), nonmedical use was associated with male sex, younger age, white race, history of use of illicit drugs, history of other drug use disorders, and history of illegal behaviors.
conclusionsThese results indicate that prescription for anxiety medications is associated with nonmedical use of these medications, although the direction of causality cannot be determined in this study. Although anxiety medications have clinical utility, greater clinical attention should be given to the potential for their abuse among patients at particular risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.