Evidence map›Paper›PMID 20595062›Full record

ReviewPharmacology, biochemistry, and behavior2010

Oxytocin as feeding inhibitor: maintaining homeostasis in consummatory behavior.

Pawel K Olszewski, Anica Klockars, Helgi B Schiöth, Allen S Levine

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Pharmacology, biochemistry, and behavior, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01891201 (Intrapartum Oxytocin Administration Affects Primitive Neonatal Reflexes), which is not on this map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
8.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01891201 completednot on this mapstarted 2011, after this paper: background citation

Intrapartum Oxytocin Administration Affects Primitive Neonatal Reflexes

Typeobservational_patient_registrySponsorPuerta de Hierro University HospitalRan2011 to 2013Enrolled98ConditionsBonding, Oxytocin, Breastfeeding, NewbornArmsOxytocin
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 92 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Central regulation of body fluid homeostasis.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2022
    Review
  10. Article
  11. Do oxytocin neurones affect feeding?Journal of neuroendocrinology · 2021
    Review
  12. Review
  13. Review
  14. The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Pawel K OlszewskiMinnesota Obesity Center, Department of Food Science and Nutrition, University of Minnesota, St. Paul, MN 55108, USA.
Anica Klockars
Helgi B Schiöth
Allen S Levine
Uppsala University · SEUniversity of Minnesota · US

Funding

Obesity and Energy Metabolism CoreP30DK050456 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BERNLOHR, DAVID A · 1995 to 2015
$17.0M
Effect of Sweet Tastants on Opioid-Melanocortin InteractionsR01DA021280 · NIDA · UNIVERSITY OF MINNESOTA · PI LEVINE, ALLEN S · 2007 to 2011
$1.4M
NIDA NIH HHS R01 DA021280NIDDK NIH HHS P30 DK050456
6 · The paper itself

Abstract

Initial studies showed that the anorexigenic peptide oxytocin (OT) regulates gastric motility, responds to stomach distention and to elevated osmolality, and blocks consumption of toxic foods. Most recently, it has been proposed to act as a mediator of general and carbohydrate-specific satiety and regulator of body weight. In the current review, we discuss the function of OT as a homeostatic inhibitor of consumption, capable of mitigating multiple aspects of ingestive behavior and energy metabolism.

Indexed as

AnimalsAnorexiaConsummatory BehaviorEnergy MetabolismFeeding BehaviorHomeostasisHumansObesityOxytocinOxytocin

Identifiers

PMID20595062
PMCPMC2952698
OpenAlexW2079035127

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.