ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2010
Undetected chronic obstructive pulmonary disease and asthma in people over 50 years with persistent cough.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Effectiveness of case finding strategies for COPD in primary care: a systematic review and meta-analysis.NPJ primary care respiratory medicine · 2015Pooled it
- Use of expert panels to define the reference standard in diagnostic research: a systematic review of published methods and reporting.PLoS medicine · 2013Pooled it
- Risk stratification for COPD diagnosis through an active search strategy in primary care.International journal of chronic obstructive pulmonary disease · 2016Observational
- Accuracy of symptoms, signs, and C-reactive protein for early chronic obstructive pulmonary disease.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012Article
- Does a decision aid help physicians to detect chronic obstructive pulmonary disease?The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Article
- COPD in primary care: a time of opportunity.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010Article
- The effect of inhalation ofJournal of the International Society of Sports NutritionArticle
- Diagnostic value of oral prednisolone test for chronic obstructive pulmonary disorders.Annals of family medicineArticle
- Airway obstruction and bronchodilator responsiveness in adults with acute cough.Annals of family medicineArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic obstructive pulmonary disease (COPD) and asthma are underdiagnosed in primary care.
aimTo determine how often COPD or asthma are present in middle-aged and older patients who consult their GP for persistent cough. DESIGN OF STUDY: A cross-sectional study in 353 patients older than 50 years, visiting their GP for persistent cough and not known to have COPD or asthma.
settingGeneral practice in the Netherlands.
methodAll participants underwent extensive diagnostic work-up, including symptoms, signs, spirometry, and body plethysmography. All results were studied by an expert panel to diagnose or exclude COPD and/or asthma. The reproducibility of the panel diagnosis was assessed by calculation of Cohen's kappa statistic in a sample of 41 participants.
resultsOf the 353 participants, 102 (29%, 95% confidence interval [CI] = 24 to 34%) were diagnosed with COPD. In 14 of these 102 participants, both COPD and asthma were diagnosed (4%, 95% CI = 2 to 7%). Asthma (without COPD) was diagnosed in 23 (7%, 95% CI = 4 to 10%) participants. Mean duration of cough was 93 days (median 40 days). The reproducibility of the expert panel was good (Cohen's kappa = 0.90).
conclusionIn patients aged over 50 years who consult their GP for persistent cough, undetected COPD or asthma is frequently present.
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