ReviewInternational psychogeriatrics2010
Prospects for delaying the rising tide of worldwide, late-life dementias.
Review in International psychogeriatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 57 citations in OpenAlex.
- Functional outcomes of multi-condition collaborative care and successful ageing: results of randomised trial.BMJ (Clinical research ed.) · 2011Trial
- Determinants of Activity Levels in African Americans With Mild Cognitive Impairment.Alzheimer disease and associated disordersTrial
- Walking stabilizes cognitive functioning in Alzheimer's disease (AD) across one year.Archives of gerontology and geriatricsTrial
- The impact of modifiable risk factor reduction on future dementia burden: a microsimulation modeling study.European journal of epidemiology · 2025Article
- Could the Early Detection of Atrial Fibrillation Reduce the Risk of Developing Dementia?Biomedicines · 2024Review
- Neuroprotective effects of hesperetin on HNutrition research and practice · 2023Article
- Brain Health Indicators Following Acute Neuro-Exergaming: Biomarker and Cognition in Mild Cognitive Impairment (MCI) after Pedal-n-Play (iPACES).Brain sciences · 2023Article
- Impact of aerobic versus resisted exercise training on systemic inflammation biomarkers and quality of Life among obese post-menopausal women.African health sciences · 2019Article
- The Association Between Central Nervous System-Active Medication Use and Fall-Related Injury in Community-Dwelling Older Adults with Dementia.Pharmacotherapy · 2019Article
- Associated factors for cognition of physically independent elderly people living in residential care facilities for the aged in Sri Lanka.BMC psychiatry · 2019Article
- The Aerobic and Cognitive Exercise Study (ACES) for Community-Dwelling Older Adults With or At-Risk for Mild Cognitive Impairment (MCI): Neuropsychological, Neurobiological and Neuroimaging Outcomes of a Randomized Clinical Trial.Frontiers in aging neuroscience · 2018Article
- Aerobic exercise improves quality of life, psychological well-being and systemic inflammation in subjects with Alzheimer's disease.African health sciences · 2016Article
- Chiropractic intern attitudes, beliefs, and future practice intentions with regard to health promotion, wellness, and preventive services.The Journal of chiropractic education · 2016Article
- The nature of behavioural correlates of healthy ageing: a twin study of lifestyle in mid to late life.International journal of epidemiology · 2014Article
- Diphenyl diselenide-supplemented diet and swimming exercise enhance novel object recognition memory in old rats.Age (Dordrecht, Netherlands) · 2014Article
- Age-specific effects of voluntary exercise on memory and the older brain.Biological psychiatry · 2013Article
- MicroRNA-195 protects against dementia induced by chronic brain hypoperfusion via its anti-amyloidogenic effect in rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Reduction of Long-Term Care Dependence After an 8-Year Primary Care Prevention Program for Stroke and Dementia: The INVADE Trial.Journal of the American Heart Association · 2012Article
- Validity and reliability of the Brazilian Portuguese version of the Australian National University - Alzheimer's Disease Risk Index (ANU-ADRI).Dementia & neuropsychologiaArticle
- Dementia care in public health in Brazil and the world: A systematic review.Dementia & neuropsychologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Worldwide, lifespan is lengthening. Concomitantly, late-life dementias are increasingly common, challenging both personal and public health internationally. After age 65, rates of dementia tend to double every five years in developed countries and every seven in developing ones. The late-life dementias, particularly Alzheimer's disease, have profound effects on aging individuals and their caregivers. Multidisciplinary research has explored the potential for various approaches to prevent or delay the onset of late-life dementias. Outlining that research, including our team's Adult Changes in Thought and Kame studies, this review concludes that delaying the onset of these dementias appears feasible, although absolute prevention may not be. Today, the most promising methods appear to include controlling vascular risk factors like hypertension and engaging in physical exercise - and possibly mental exercise. If people can delay the onset of dementias, they can lead more fulfilling lives for longer, spending less time suffering from dementia and letting their families spend less time coping with the disease. It is possible that trends toward more knowledge-based societies, where cognitive health is so vital, may increasingly exert evolutionary pressure favoring larger and healthier brains - and a "compression of cognitive morbidity" - well into old age. Public health's great triumph, increased lifespan, should give more of the world's people the reward of many years of dementia-free life. Rather than the personal difficulties and public health burdens of many years of functional impairment, dependency, and suffering with dementia, some interventions may delay the onset of Alzheimer's disease and other dementias.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.