ArticlePharmacy world & science : PWS2010
Detection of drug related problems in an interdisciplinary health care model for rural areas in Germany.
Article in Pharmacy world & science : PWS, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01401582 (Dementia), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dementia: Life- and Personcentered Help in Germany
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of pharmacist-led home medicines review services on drug-related problems among the elderly population: a systematic review.Epidemiology and health · 2019Pooled it
- Medication review and reconciliation with cooperation between pharmacist and general practitioner and the benefit for the patient: a systematic review.British journal of clinical pharmacology · 2012Pooled it
- Medication management for people with dementia in primary care: description of implementation in the DelpHi study.BMC geriatrics · 2013Trial
- Trial
- Article
- Unprescribed and unnoticed: Retrospective chart review of adverse events of interactions between antidepressants and over-the-counter drugs.Frontiers in pharmacology · 2022Article
- Healthcare Provider Perspectives on Digital and Interprofessional Medication Management in Chronically Ill Older Adults of Turkish Descent in Germany: A Qualitative Structuring Content Analysis.Frontiers in public health · 2022Article
- Prevalence of drug interactions in elderly patients with multimorbidity in primary care.International journal of clinical pharmacy · 2017Review
- The pharmacist and the EHR.Journal of the American Medical Informatics Association : JAMIA · 2017Article
- Effects of a three party healthcare network on the incidence levels of drug related problems.International journal of clinical pharmacy · 2013Article
- Cooperation between community pharmacists and general practitioners in eastern Germany: attitudes and needs.International journal of clinical pharmacy · 2013Article
- Prevalence and determinants of controlled hypertension in a German population cohort.BMC public health · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe disparity between an increasing complexity of patients' treatment and the declining number of general practitioners (GP) require action. The AGnES-concept (general practitioner-relieving, community-based, e-health assisted, systemic intervention) is based on the delegation of original physician-activities to qualified AGnES-practice assistants. Purposes of AGnES part 1 were to determine the feasibility of community-based home medication reviews (HMR) and the establishment of a health professional network to identify drug related problems (DRP) in the domicile of elderly patients. Two consecutive studies (AGNES 2 + 3) were conducted to implement HMR.
settingGeneral practices on the isle of Rugia in Mecklenburg-Western Pomerania, a German rural area. Patients who receive regular home visits by their GP were addressed.
methodStudy-instruments for the feasibility study (AGnES 1) were designed by an expert panel and modified for the implementation (AGnES 2 + 3) studies. HMR were conducted by additionally qualified AGnES-practice assistants regarding DRP like drug-drug interaction (DDI), adverse drug reactions (ADR), and compliance. DRP-selection was inspired by the coding system Pi-Doc. Pharmacists checked DRP and intervened, if necessary. 18 (AGnES 1) and 60 (AGnES 2 + 3) geriatric patients received a minimum of two home visits by an AGnES-practice assistant.
main outcome measureFeasibility was assessed by patients' satisfaction with care provided by the AGnES-practice assistant. For implementation reported DRP and the conducted interventions were evaluated.
resultsDuring AGnES 1 a documentation sheet was developed and tested. 56 potential DDI were identified. 37 of 112 drugs which caused potential interactions were attributed to OTC medication and food components. 84% of respondents judged the systematic evaluation of their pharmacotherapy as helpful. During AGnES 2 + 3 local pharmacists identified DDIs in 45% of patients. Seven patients (11.6%) reported at least one ADR attributable to their current medication. Those patients who received a second HMR (n = 29) during AGnES 2 + 3 rated the HMR as reasonable 65.5% (n = 19), and partly reasonable 24.1% (n = 7).
conclusionsBy comprehensive HMR conducted by AGnES-practice assistants in delegation of the patients' GPs in cooperation with local pharmacists we could identify a considerable prevalence of DRP under real-life conditions. Further studies should recruit more participants including a control group with usual care.
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