Evidence map›Paper›PMID 20593010›Full record

ArticleTherapeutic advances in gastroenterology2009

Effective treatment of chronic radiation proctitis using radiofrequency ablation.

Chao Zhou, Desmond C Adler, Laren Becker, Yu Chen, Tsung-Han Tsai, Marisa Figueiredo, Joseph M Schmitt, James G Fujimoto, Hiroshi Mashimo

Open access · greenAbstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Review
  4. Article
  5. Update on the management of the gastrointestinal effects of radiation.World journal of gastrointestinal oncology · 2021
    Review
  6. Review
  7. Observational
  8. Article
  9. Management of Radiation Proctitis.Digestive diseases and sciences · 2018
    Review
  10. Radiofrequency ablation for gastric antral vascular ectasia and radiation proctitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2017
    Article
  11. Review
  12. Review
  13. Review
  14. Chronic haemorrhagic radiation proctitis: A review.World journal of gastrointestinal surgery · 2016
    Review
  15. Exploring the Management of Radiation Proctitis in Current Clinical Practice.Journal of clinical and diagnostic research : JCDR · 2016
    Review
  16. Pelvic radiation disease: Updates on treatment options.World journal of clinical oncology · 2015
    Review
  17. Review
  18. [Endoscopic management of lower gastrointestinal bleeding].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2015
    Review
  19. Emerging indications of endoscopic radiofrequency ablation.United European gastroenterology journal · 2015
    Review
  20. Radiation proctopathy.Clinics in colon and rectal surgery · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Chao ZhouDepartment of Electrical Engineering and Computer Science and Research Laboratory of Electronics Massachusetts Institute of Technology, Cambridge, MA, USA.
Desmond C Adler
Laren Becker
Yu Chen
Tsung-Han Tsai
Marisa Figueiredo
Joseph M Schmitt
James G Fujimoto
Hiroshi Mashimo
Massachusetts Institute of Technology · USVA Boston Healthcare System · USHarvard University · USPhoton Imaging (United States) · US

Funding

OPTICAL BIOPSY USING OPTICAL COHERENCE TOMOGRAPHYR01CA075289 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI FUJIMOTO, JAMES G, MASHIMO, HIROSHI · 1997 to 2018
$4.8M
NCI NIH HHS R01 CA075289
6 · The paper itself

Abstract

Endoscopic argon plasma coagulation and bipolar electrocautery are currently preferred treatments for chronic radiation proctitis, but ulcerations and strictures frequently occur. Radiofrequency ablation (RFA) has been successful for mucosal ablation in the esophagus. Here we report the efficacy of RFA with the BarRx Halo(90) system in three patients with bleeding from chronic radiation proctitis. In all cases, the procedure was well tolerated and hemostasis was achieved after 1 or 2 RFA sessions. Re-epithelialization of squamous mucosa was observed over areas of prior hemorrhage. No stricturing or ulceration was seen on follow-up up to 19 months after RFA treatment. Real-time endoscopic optical coherence tomography (EOCT) visualized epithelialization and subsurface tissue microvasculature pre- and post-treatment, demonstrating its potential for follow-up assessment of endoscopic therapies.

Identifiers

PMID20593010
PMCPMC2893353
OpenAlexW2129520988

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.