Evidence map›Paper›PMID 20592927›Full record

ArticleKorean journal of radiology

Gadoxetic acid (Gd-EOB-DTPA)-enhanced MRI versus gadobenate dimeglumine (Gd-BOPTA)-enhanced MRI for preoperatively detecting hepatocellular carcinoma: an initial experience.

Yulri Park, Seong Hyun Kim, Seung Hoon Kim, Yong Hwan Jeon, Jongmee Lee, Min Ju Kim, Dongil Choi, Won Jae Lee, Heejung Kim, Ji Hyun Koo and 1 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
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  9. Multiparametric MR Imaging in Abdominal Malignancies.Magnetic resonance imaging clinics of North America · 2016
    Review
  10. Imaging of HCC-Current State of the Art.Diagnostics (Basel, Switzerland) · 2015
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Yulri ParkDepartment of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea.
Seong Hyun Kim
Seung Hoon Kim
Yong Hwan Jeon
Jongmee Lee
Min Ju Kim
Dongil Choi
Won Jae Lee
Heejung Kim
Ji Hyun Koo
Hyo Keun Lim
Samsung Medical Center · KRSungkyunkwan University · KRKangwon National University Hospital · KRKorea University · JPKorea University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was designed to compare the diagnostic performance of gadoxetic acid-enhanced magnetic resonance imaging (MRI) with gadobenate dimeglumine-enhanced MRI for preoperatively detecting hepatocellular carcinoma (HCC). MATERIALS AND

methodsEighteen consecutive patients (17 men and one woman, age range: 31-73 years) with 22 HCCs underwent examinations with gadoxetic acid enhanced MRI and gadobenate dimeglumine-enhanced MRI on a 3.0-Tesla unit. The diagnosis of HCC was established after surgical resection and pathological conformation. Three observers independently reviewed each MR image in a random order on a tumor-by-tumor basis. The diagnostic accuracy of these techniques for the detection of HCC was assessed by performing an alternative free-response receiver operating characteristic (ROC) analysis. The sensitivity and positive predictive values were evaluated.

resultsThe average value of the area under the ROC curve (Az) for gadoxetic acid enhanced MRI (0.887) was not significantly different from the Az (0.899) for gadobenate dimeglumine-enhanced MRI (p > 0.05). The overall sensitivities of gadoxetic acid enhanced MRI and gadobenate dimeglumine-enhanced MRI were 80% and 83%, respectively, with no significant difference (p > 0.05). The differences of the positive predictive values for the two contrast agents for each observer were not statistically significant (p > 0.05).

conclusionThe diagnostic performance of gadoxetic acid-enhanced MRI and gadobenate dimeglumine-enhanced MRI for preoperatively detecting HCC is quite similar.

Indexed as

Gadolinium DTPAOrganometallic CompoundsAdultAgedCarcinoma, HepatocellularFemaleHumansImage Interpretation, Computer-AssistedLiver NeoplasmsMagnetic Resonance ImagingMaleMeglumineMiddle AgedPredictive Value of TestsROC CurveSensitivity and Specificitygadobenic acidGadolinium DTPAgadolinium ethoxybenzyl DTPAMeglumineOrganometallic CompoundsGadobenate dimeglumine-enhanced MRIGadoxetic acid-enhanced MRIHepatocellular carcinoma (HCC)

Identifiers

PMID20592927
PMCPMC2893314
OpenAlexW2171132804

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.