Evidence map›Paper›PMID 20591807›Full record

Trial reportOncology nursing forum2010

Pilot study of cranial stimulation for symptom management in breast cancer.

Debra E Lyon, Christine Schubert, Ann Gill Taylor

Open access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Oncology nursing forum, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Study of symptom clusters in brain tumor patients 2 weeks after craniotomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  2. Review
  3. Article
  4. Article
  5. Biological Basis for the Clustering of Symptoms.Seminars in oncology nursing · 2016
    Review
  6. Article
  7. Breast Cancer EDGE Task Force Outcomes: Clinical Measures of Pain.Rehabilitation oncology (American Physical Therapy Association. Oncology Section) · 2014
    Article
  8. Review
  9. Brain stimulation in posttraumatic stress disorder.European journal of psychotraumatology · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Debra E LyonSchool of Nursing, Virginia Commonwealth University, Richmond, USA. delyon@vcu.edu
Christine Schubert
Ann Gill Taylor
Virginia Commonwealth University · USUniversity of Virginia · US

Funding

Physical Health, Depressive Symptoms, Happiness, and Maternal CompetenceP20NR008988 · NINR · VIRGINIA COMMONWEALTH UNIVERSITY · PI MCCAIN, NANCY L · 2004 to 2008
$1.5M
Cranial Stimulation for Chemotherapy Symptoms in Breast CancerR01CA127446 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI MCGUIRE, DEBORAH B. · 2009 to 2013
$1.5M
Cranial Stimulation for Chemo Symptoms in Breast CancerR21CA106149 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI LYON, DEBRA E · 2003 to 2004
$453k
NCI NIH HHS R01 CA127446NCI NIH HHS R21 CA106149NINR NIH HHS P20 NR008988
6 · The paper itself

Abstract

PURPOSE/

objectivesTo examine the feasibility, relationships among variables, and preliminary outcomes of a self-directed complementary modality, cranial electrical stimulation (CES), for symptom management in women receiving chemotherapy for breast cancer.

designBiobehavioral pilot feasibility study.

settingTwo university-based cancer centers. SAMPLE: 36 women with stage I-IIIA breast cancer scheduled to receive chemotherapy.

methodsData were collected via interview, questionnaires, and interactive voice technology (IVR). Biomarkers were measured from a blood sample taken prior to the initial chemotherapy. MAIN RESEARCH VARIABLES: Symptoms of depression, anxiety, fatigue, pain, and sleep disturbances; biomarkers (proinflammatory cytokines interleukin-6, tumor necrosis factor alpha [TNF-alpha], interleukin-1 beta) and C-reactive protein [CRP]); and CES.

findingsCES appears to be a safe and acceptable modality during chemotherapy. Recruitment and retention were adequate. IVR was associated with missing data. Symptoms of depression, anxiety, fatigue, and sleep disturbances were highly correlated with each other, and most symptoms were correlated with CRP at baseline. Depression and TNF-alpha had a positive, significant relationship. Levels of depression increased over time and trended toward less increase in the CES group; however, the differences among groups were not statistically significant.

conclusionsThe data support the feasibility of CES. Further testing in larger samples is needed to examine the efficacy of CES for symptom management of multiple, concurrent symptoms and to further develop the biobehavioral framework. IMPLICATIONS FOR NURSING: Interventions that are effective at minimizing more than one target symptom are especially needed to provide optimal symptom management for women with breast cancer.

Indexed as

AdultAnthracyclinesAntineoplastic Combined Chemotherapy ProtocolsAnxietyBreast NeoplasmsDepressionFatigueFeasibility StudiesFemaleHumansMiddle AgedPainPain ManagementPatient SatisfactionPilot ProjectsProspective StudiesAnthracyclines

Identifiers

PMID20591807
PMCPMC3061342
OpenAlexW2026392526

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.