Evidence map›Paper›PMID 20590901›Full record

GuidelineHPB : the official journal of the International Hepato Pancreato Biliary Association2010

Pretreatment assessment of hepatocellular carcinoma: expert consensus statement.

Jean-Nicolas Vauthey, Elijah Dixon, Eddie K Abdalla, W Scott Helton, Timothy M Pawlik, Bachir Taouli, Antoine Brouquet, Reid B Adams, American Hepato-Pancreato-Biliary Association, Society of Surgical Oncology and 1 more

Open access · bronzeAbstract readConsensus StatementPractice Guideline
In one paragraph

Guideline in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 208 citations in OpenAlex.

  1. Trial
  2. Article
  3. Establishing the Minimum Future Liver Remnant Volume for Safe Hepatectomy.Journal of the American College of Surgeons · 2026
    Article
  4. Article
  5. Article
  6. Article
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  10. Review
  11. Hepatocellular Carcinoma from a Hepatologist's Perspective.Seminars in interventional radiology · 2023
    Review
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  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Jean-Nicolas VautheyDepartment of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA. jvauthey@mdanderson.org
Elijah Dixon
Eddie K Abdalla
W Scott Helton
Timothy M Pawlik
Bachir Taouli
Antoine Brouquet
Reid B Adams
American Hepato-Pancreato-Biliary Association
Society of Surgical Oncology
Society for Surgery of the Alimentary Tract
The University of Texas MD Anderson Cancer Center · USIcahn School of Medicine at Mount Sinai · USJohns Hopkins Medicine · USUniversity of Calgary · CAUniversity of Virginia Health System · USYale New Haven Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Staging of hepatocellular carcinoma (HCC) is complex and relies on multiple factors including tumor extent and hepatic function. No single staging system is applicable to all patients with HCC. The staging of the American Joint Committee on Cancer / International Union for Cancer Control should be used to predict outcome following resection or liver transplantation. The Barcelona Clinic Liver Cancer scheme is appropriate in patients with advanced HCC not candidate for surgery. Dual phase computed tomography or magnetic resonance imaging can be used for pretreatment assessment of tumor extent but the accuracy of these methods remains poor to characterize < 1 cm lesions. Assessment of tumor response should not rely only on tumor size and new imaging methods are available to evaluate response to therapy in HCC patients. Liver volumetry is part of the preoperative assessment of patients with HCC candidate for resection as it reflects liver function. Preoperative portal vein embolization is indicated in patients with small future liver remnant (≤ 20% in normal liver; ≤ 40% in fibrotic or cirrhotic liver). Tumor size is not a contraindication to liver resection. Liver resection can be proposed in selected patients with multifocal HCC. Besides tumor extent, surgical resection of HCC may be performed in selected patients with chronic liver disease.

Indexed as

Neoplasm StagingBiomarkers, TumorCarcinoma, HepatocellularChemoembolization, TherapeuticChemotherapy, AdjuvantHepatectomyHumansLiver Function TestsLiver NeoplasmsMagnetic Resonance ImagingNeoadjuvant TherapyPatient SelectionPredictive Value of TestsRadiotherapy, AdjuvantSeverity of Illness IndexTomography, X-Ray ComputedBiomarkers, Tumor

Identifiers

PMID20590901
PMCPMC2951814
OpenAlexW2109820748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.