ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2010
Liver retransplantation in adults: a single-centre, 25-year experience.
Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 106 citations in OpenAlex.
- Posttransplant muscle mass measured by urinary creatinine excretion rate predicts long-term outcomes after liver transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019Trial
- Early Response to Therapeutic Plasma Exchange as a Prognostic Indicator in Pediatric Liver Transplant Recipients with Early Allograft Dysfunction.Pediatric transplantation · 2026Article
- Comparison of time-to-event machine learning models in predicting biliary complication and mortality rate in liver transplant patients.Scientific reports · 2025Article
- Indications and Outcomes with Liver Retransplantation in 2025.Digestive diseases and sciences · 2025Review
- The impact of macro- and micro-steatosis on the outcomes of patients who undergo liver transplant: Analysis of the UNOS-STAR database.Liver international : official journal of the International Association for the Study of the Liver · 2024Article
- A single center analysis of long-term outcomes and survival related risk factors in liver retransplantation.Hepatobiliary surgery and nutrition · 2024Article
- Antiplatelet Prophylaxis Reduces the Risk of Early Hepatic Artery Thrombosis Following Liver Transplantation in High-Risk Patients.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Indications and outcomes of liver retransplantation in three medical centers.Revista do Colegio Brasileiro de Cirurgioes · 2024Article
- The BAR Score Predicts and Stratifies Outcomes Following Liver Retransplantation: Insights From a Retrospective Cohort Study.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Mortality and Morbidity Among Adult Liver Retransplant Recipients.Digestive diseases and sciences · 2023Article
- Graft-recipient-weight ratio and lowered immunosuppression is important for the success of adult liver retransplantation.Scientific reports · 2023Article
- The Yield of Routine Post-Operative Doppler Ultrasound to Detect Early Post-Liver Transplantation Vascular Complications.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Factors affecting survival after liver retransplantation: a systematic review and meta-analysis.Frontiers in transplantation · 2023Review
- Outcomes of Adult Liver Retransplantation: A Canadian National Database Analysis.Canadian journal of gastroenterology & hepatology · 2022Article
- Liver Re-transplantation in Adults: Indications and Outcomes Analysis of a 23-year Experience in a Single Center in Argentina.International journal of organ transplantation medicine · 2022Article
- RISK FACTORS ASSOCIATED WITH HEPATIC ARTERY THROMBOSIS: ANALYSIS OF 1050 LIVER TRANSPLANTS.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2021Article
- Impact of sarcopenia on mortality in patients undergoing liver re-transplantation.World journal of hepatology · 2020Article
- Adult liver transplantation: UK clinical guideline - part 2: surgery and post-operation.Frontline gastroenterology · 2020Review
- Excellent Contemporary Graft Survival for Adult Liver Retransplantation: An Australian and New Zealand Registry Analysis From 1986 to 2017.Transplantation direct · 2019Article
- Retransplantation in Late Hepatic Artery Thrombosis: Graft Access and Transplant Outcome.Transplantation direct · 2017Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRetransplantation is the only form of treatment for patients with irreversible graft failure. The aim of this study was to analyse a single centre's experience of the indications for and outcomes of retransplantation.
methodsA total of 196 patients who underwent liver retransplantation using 225 grafts, between January 1982 and July 2007, were included in the study. The following parameters were analysed: patient demographics; primary diagnosis; distribution of retransplantation over different time periods; indications for retransplantation; time interval to retransplantation, and overall patient and graft survival.
resultsOf the 2437 primary orthotopic liver transplantations, 196 patients (8%) required a first regraft, 23 patients (1%) a second regraft and six patients (0.25%) a third regraft. Autoimmune hepatitis was the most common primary diagnosis for which retransplantation was required (12.7% of primary transplantations). The retransplantation rate declined from 12% at the beginning of our programme to 7.6% at the end of the study period. The most common indication for retransplantation was hepatic artery thrombosis (31.6%). Nearly two-thirds of the retransplantations were performed within 6 months of the primary transplantation. The 1-, 3-, 5- and 10-year patient survival rates following first retransplantation were 66%, 61%, 57% and 47%, respectively. Five-year survival after second retransplantation was 40%. None of the patients have yet survived 3 years after a third regraft. Donor age of < or =55 years and a MELD (Model for End-stage Liver Disease) score of < or =23 were associated with better outcome following retransplantation.
conclusionsFirst retransplantation was associated with good longterm survival. There was no survival benefit following second and third retransplantations. A MELD score of < or =23 and donor age of < or =55 years correlated with better outcome following retransplantation.
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