Trial reportJournal of the American Veterinary Medical Association2010
Use of an activity monitor to detect response to treatment in dogs with osteoarthritis.
Trial report in Journal of the American Veterinary Medical Association, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 1 synthesis or guideline pooled it, 136 citations in OpenAlex.
- Systematic Review of Outcome Measures Reported in Clinical Canine Osteoarthritis Research.Veterinary surgery : VS · 2016Pooled it
- Evaluation of intra-articular injection of collagen-elastin hydrogel microparticles for managing osteoarthritis-associated elbow pain in dogs: a double-blind, positive-controlled clinical trial.Frontiers in veterinary science · 2026Trial
- Caregiver placebo effect in analgesic clinical trials for cats with naturally occurring degenerative joint disease-associated pain.The Veterinary record · 2017Trial
- The Use of Functional Data Analysis to Evaluate Activity in a Spontaneous Model of Degenerative Joint Disease Associated Pain in Cats.PloS one · 2017Trial
- Evaluation of Clinical Metrology Instrument in Dogs with Osteoarthritis.Journal of veterinary internal medicine · 2016Trial
- A canine-specific anti-nerve growth factor antibody alleviates pain and improves mobility and function in dogs with degenerative joint disease-associated pain.BMC veterinary research · 2015Trial
- Intrathecal substance P-saporin in the dog: efficacy in bone cancer pain.Anesthesiology · 2013Trial
- Effect of analgesic therapy on clinical outcome measures in a randomized controlled trial using client-owned dogs with hip osteoarthritis.BMC veterinary research · 2012Trial
- Clinical validity of outcome pain measures in naturally occurring canine osteoarthritis.BMC veterinary research · 2012Trial
- Percutaneous Cementoplasty as a Monotherapy in the Treatment of Appendicular Osteosarcoma in Ten Dogs.Animals : an open access journal from MDPI · 2026Article
- From dyadic deco-construction to reco-construction: a framework for the human-osteoarthritic dog relationship.Frontiers in veterinary science · 2026Review
- Actical Accelerometers as a Clinical Tool for the Monitoring of Sleeping and Resting Periods in Individual Dogs.Animals : an open access journal from MDPI · 2025Article
- Physical Activity Monitors in Companion Animal Chronic Pain Research-A Review Focused on Osteoarthritis Pain.Animals : an open access journal from MDPI · 2025Review
- Collagen Hydrolysates as Nutritional Support in Canine Osteoarthritis: A Narrative Review.Journal of animal physiology and animal nutrition · 2025Review
- A Review of the Monitoring Techniques Used to Detect Oestrus in Sows.Animals : an open access journal from MDPI · 2025Review
- Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.Frontiers in veterinary science · 2025Article
- Estimated activity levels in dogs at population scale with linear and causal modeling.Frontiers in veterinary science · 2025Article
- Utility of PLUS CYCLE to measure physical activity and sleep duration and detect postoperative sleep disturbances in hospitalized dogs.PloS one · 2025Article
- Assessment of horse behavior using an activity monitoring device used for cats and dogs.Journal of equine science · 2024Article
- The Use of Triaxial Accelerometers and Machine Learning Algorithms for Behavioural Identification in Domestic Dogs (Sensors (Basel, Switzerland) · 2024Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo determine whether an activity monitor (AM) could be used to detect changes in activity in dogs with osteoarthritis treated with carprofen or a placebo.
designRandomized controlled trial. ANIMALS: 70 dogs with no clinically important abnormalities other than osteoarthritis for which they were not currently being treated. PROCEDURES: Dogs wore an AM continuously for 21 days. On days 8 through 21, the dogs were treated with carprofen (n = 35) or a placebo (35). Total activity counts for days 1 through 7 (baseline) were compared with total activity counts for days 15 through 21 (endpoint). The change in total activity count from baseline to endpoint was assessed within each treatment group as well as between groups. Linear regression analysis was performed to test for an association between treatment and percentage change in activity counts while controlling for other variables.
resultsFor placebo-treated dogs, median baseline total activity count was not significantly different from median endpoint total activity count (1,378,408 vs 1,310,112, respectively). For dogs receiving carprofen, there was a significant increase in median activity count from baseline to endpoint (1,276,427 vs 1,374,133). When age and baseline activity counts were controlled for, dogs in the carpofen-treated group had a 20% increase in activity counts, compared with placebo-treated dogs (95% confidence interval, 10% to 26%). CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that the AM used in the present study may be a valid outcome assessment tool for documenting improved activity associated with treatment in dogs with osteoarthritis.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.