Evidence map›Paper›PMID 20590431›Full record

ReviewAnnual review of genomics and human genetics2010

Patents in genomics and human genetics.

Robert Cook-Deegan, Christopher Heaney

Open access · hybridAbstract readReview
In one paragraph

Review in Annual review of genomics and human genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
15.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 106 citations in OpenAlex.

  1. Article
  2. Trade, intellectual property, and the public health bearing.Health systems (Basingstoke, England) · 2023
    Article
  3. Article
  4. A survey of direct-to-consumer genotype data, and quality control tool (Computational and structural biotechnology journal · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Eteplirsen in the treatment of Duchenne muscular dystrophy.Drug design, development and therapy · 2017
    Review
  11. Myriad's impact on gene patents.Nature biotechnology · 2016
    Article
  12. Article
  13. The 2014 Varsity Medical Ethics Debate: should we allow genetic information to be patented?Philosophy, ethics, and humanities in medicine : PEHM · 2015
    Article
  14. The translational potential of research on the ethical, legal, and social implications of genomics.Genetics in medicine : official journal of the American College of Medical Genetics · 2015
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Robert Cook-DeeganInstitute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA. gelp@duke.edu
Christopher Heaney
Duke University · US

Funding

The Management and Organization Core will be administered by the Center for GenomP50HG003391 · NHGRI · DUKE UNIVERSITY · PI BESKOW, LAURA M. · 2004 to 2014
$9.9M
NHGRI NIH HHS P50 HG003391Wellcome Trust
6 · The paper itself

Abstract

Genomics and human genetics are scientifically fundamental and commercially valuable. These fields grew to prominence in an era of growth in government and nonprofit research funding, and of even greater growth of privately funded research and development in biotechnology and pharmaceuticals. Patents on DNA technologies are a central feature of this story, illustrating how patent law adapts-and sometimes fails to adapt-to emerging genomic technologies. In instrumentation and for therapeutic proteins, patents have largely played their traditional role of inducing investment in engineering and product development, including expensive post-discovery clinical research to prove safety and efficacy. Patents on methods and DNA sequences relevant to clinical genetic testing show less evidence of benefits and more evidence of problems and impediments, largely attributable to university exclusive licensing practices. Whole-genome sequencing will confront uncertainty about infringing granted patents, but jurisprudence trends away from upholding the broadest and potentially most troublesome patent claims.

Indexed as

GenomicsPatents as TopicDNAGenesGenetics, MedicalGenetic TechniquesHumansDNA

Identifiers

PMID20590431
PMCPMC2935940
OpenAlexW2110820132

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.