ArticleKorean journal of anesthesiology2010
Anaphylactoid reaction after injection of ketorolac in a loading dose for patient-controlled analgesia -A case report-.
Article in Korean journal of anesthesiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- Article
- Clinical Presentations and Characteristics of NSAIDs Hypersensitivity in a Tertiary Care Hospital in Indonesia: A Case Series.International medical case reports journal · 2025Article
- Ketorolac-induced anaphylaxis following oral administration: a case series.Annals of medicine and surgery (2012) · 2023Article
- Anaphylaxis as a Rare Side Effect of Ketorolac; a Case Report.Archives of academic emergency medicine · 2020Article
- Prescription of potentially inappropriate medication to older patients presenting to the emergency department: a nationally representative population study.Scientific reports · 2018Article
- Drug overdose due to malfunction of a patient-controlled analgesia machine -A case report-.Korean journal of anesthesiology · 2013Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anaphylaxis is a severe and life-threatening systemic hypersensitivity reaction. Ketorolac is a popular drug used for patient-controlled analgesia. Although anaphylactic reaction to ketorolac has not been frequently reported, it can develop by way of several mechanisms. A 41-year-old male patient was scheduled for laparoscopic correction of a perforated gastric ulcer. Emergency surgery was performed under general anesthesia with no complications. Near the end of anesthesia administration, ketorolac in a loading dose was administered intravenously in order to launch patient-controlled analgesia. Following injection, urticaria-like skin lesions, including rashes and wheels appeared systemically; tachycardia and breathing difficulty with oxygen desaturation also developed. Through additional inquiry into the patient's drug history, past experience with ibuprofen allergy was identified. Antihistamine, steroid, and aminophylline were administered, and continuous positive airway pressure by full facial mask was applied to relieve bronchospastic symptoms. The patient recovered without further complications.
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