ArticleCase reports in medicine2010
Leiomyosarcoma arising in the pancreatic duct: a case report and review of the current literature.
Article in Case reports in medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Clinical characteristics and prognosis of primary leiomyosarcoma of the pancreas: a systematic review.World journal of surgical oncology · 2013Pooled it
- Rare Solid Pancreatic Lesions on Cross-Sectional Imaging.Diagnostics (Basel, Switzerland) · 2023Review
- Could the burden of pancreatic cancer originate in childhood?World journal of gastroenterology · 2021Review
- Pancreatic Leiomyosarcoma With Schistosomiasis Hematobia: A Case Report and Literature Review.Frontiers in oncology · 2021Article
- Pancreatic leiomyosarcoma: a diagnostic challenge and literature review.BMJ case reports · 2019Review
- Primary leiomyosarcoma of the pancreas: report of a case treated by local excision and review of the literature.Surgical case reports · 2015Article
- Metastatic leiomyosarcoma of the intrapancreatic bile duct.Journal of the Korean Surgical Society · 2013Article
- Leiomyosarcoma of the Pancreas with Liver Metastases as a Paradigm of Multimodality Treatment: Case Report and Review of the Literature.Journal of gastrointestinal cancer · 2012Review
- [Leiomyosarcoma of the pancreas: a tumor with poor prognosis--clinical case and review of the literature].The Pan African medical journal · 2012Review
- Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Context. Leiomyosarcomas are rare malignant smooth muscle tumors that may arise in any organ or tissue that contains smooth muscle, commonly within the gastrointestinal tract. They are most often found in the stomach, large and small intestines, and retroperitoneum. Primary pancreatic leiomyosarcoma is extremely rare, and to the best of our knowledge only 30 cases have been reported in the world literature since 1951. Our case represents the first to have a clear origin from the main pancreatic duct. Case Report. This case was diagnosed in a large, tertiary care center in Tampa, Florida. Pertinent information was obtained from chart review and interdepartmental collaboration. A mass in the tail of the pancreas was identified with large pleomorphic and spindle-shaped cells. Immunohistochemistry for vimentin, smooth muscle actin, and desmin was positive. All remaining immunohistochemical markers performed were negative. The tumor clearly originated from the pancreatic duct wall, filled and expanded the duct lumen, and was covered with a layer of benign biliary epithelium. Conclusion. Leiomyosarcoma of the pancreas is an extremely rare malignancy with few reported cases in the literature. The prognosis is poor, and treatment consists of alleviating symptoms and pain management. To our knowledge, this represents the first reported case demonstrating clear origin of a leiomyosarcoma from the pancreatic duct.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.