Evidence map›Paper›PMID 20587728›Full record

ArticleDiabetes care2010

Diabetes and cancer: a consensus report.

Edward Giovannucci, David M Harlan, Michael C Archer, Richard M Bergenstal, Susan M Gapstur, Laurel A Habel, Michael Pollak, Judith G Regensteiner, Douglas Yee

3 registry-linked trialsOpen access · hybridAbstract readConsensus Statement
In one paragraph

Article in Diabetes care, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 997 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
997citing papers in PubMed, 5 pooled it
54.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03477162 early_phase1terminatednot on this mapstarted 2018, after this paper: background citation

Metformin Pharmacology in Human Cancers

TypeinterventionalSponsorDartmouth-Hitchcock Medical CenterRan2018 to 2021Enrolled18ConditionsThoracic NeoplasmArmsMetformin
NCT04477694 unknown statusnot on this mapstarted 2020, after this paper: background citation

The Effect of Diabetes Mellitus on Hemodynamics, Procedure Times, Anesthetic Consumption and Complications in Colonoscopy Under Sedoanalgesia

TypeobservationalSponsorBaskent UniversityRan2020 to 2023Enrolled100ConditionsDiabetes Mellitus, Type 2, SedoanalgesiaArmscolonoscopy under sedoanalgesia
NCT05326984 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia

TypeinterventionalSponsorHospital General de MexicoRan2021 to 2023Enrolled20ConditionsAcute Lymphoblastic LeukemiaArmsMetformin
3 · Its place in the literature

Who cites it

997 citing papers in PubMed, 5 syntheses or guidelines pooled it, 2,221 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Pooled it
  6. Trial
  7. The Bidirectional Relationship Between Diabetes and Cancer: Mechanistic Insights, Epigenetic Intermediaries, and Therapeutic Approaches.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Observational
  20. Review

937 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 2 countries.

Edward GiovannucciDepartment of Nutrition, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA. egiovann@hsph.harvard.edu
David M Harlan
Michael C Archer
Richard M Bergenstal
Susan M Gapstur
Laurel A Habel
Michael Pollak
Judith G Regensteiner
Douglas Yee
American Cancer Society · USHarvard University · USKaiser Permanente · USMcGill University · CAPalmetto Hematology Oncology · USPark Nicollet Clinic · USUniversity of Colorado Denver · USUniversity of Massachusetts Chan Medical School · USUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidemiologic evidence suggests that cancer incidence is associated with diabetes as well as certain diabetes risk factors and diabetes treatments. This consensus statement of experts assembled jointly by the American Diabetes Association and the American Cancer Society reviews the state of science concerning 1) the association between diabetes and cancer incidence or prognosis, 2) risk factors common to both diabetes and cancer, 3) possible biologic links between diabetes and cancer risk, and 4) whether diabetes treatments influence risk of cancer or cancer prognosis. In addition, key unanswered questions for future research are posed.

Indexed as

Diabetes MellitusHumansHypoglycemic AgentsIncidenceNeoplasmsPrognosisRisk FactorsHypoglycemic Agents

Identifiers

PMID20587728
PMCPMC2890380
OpenAlexW2104195235

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.