Trial reportDiabetes care2010
Potential additional effect of omentectomy on metabolic syndrome, acute-phase reactants, and inflammatory mediators in grade III obese patients undergoing laparoscopic Roux-en-Y gastric bypass: a randomized trial.
Trial report in Diabetes care, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02641925 (The Effect of Visceral Fat Removal for Gastric Cancer Patients With Metabolic Syndrome, Randomized Pilot Study), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Visceral Fat Removal for Gastric Cancer Patients With Metabolic Syndrome, Randomized Pilot Study: Omentectomy for Metabolic Syndrome (OMS)
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- Metabolic aspects of surgical subcutaneous fat removal: An umbrella review and implications for future research.Biomolecules & biomedicine · 2023Pooled it
- A prospective randomized study comparing patients with morbid obesity submitted to sleeve gastrectomy with or without omentectomy.Obesity surgery · 2013Trial
- The effects of an amino acid supplement on glucose homeostasis, inflammatory markers, and incretins after laparoscopic gastric bypass.Journal of the American College of Surgeons · 2011Trial
- Omentectomy added to Roux-en-Y gastric bypass surgery: a randomized, controlled trial.Surgery for obesity and related diseases : official journal of the American Society for Bariatric SurgeryTrial
- Visceral adiposity, metabolic health and aging.Nature aging · 2026Review
- Type 2 Diabetes Mellitus, Non-Alcoholic Fatty Liver Disease, and Metabolic Repercussions: The Vicious Cycle and Its Interplay with Inflammation.International journal of molecular sciences · 2023Review
- Mesenteric fat cryolipolysis attenuates insulin resistance in the Ossabaw swine model of the metabolic syndrome.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2023Article
- Effect of Ileal Transposition (IT) on Angiopoietin-Like Protein-8 (ANGPTL8) and Pentraxin (PTX3) Plasma Level in Sprague-Dawley Rats Fed High-Fat Diet (HFD).International journal of endocrinology · 2021Article
- A comparison of the associations between adiposity and lipids in Malawi and the United Kingdom.BMC medicine · 2020Article
- Review
- HIV and antiretroviral therapy-related fat alterations.Nature reviews. Disease primers · 2020Review
- Sex and area differences in the association between adiposity and lipid profile in Malawi.BMJ global health · 2019Article
- More than an Anti-diabetic Bariatric Surgery, Metabolic Surgery Alleviates Systemic and Local Inflammation in Obesity.Obesity surgery · 2018Review
- Mesenteric visceral lipectomy using tissue liquefaction technology reverses insulin resistance and causes weight loss in baboons.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2018Article
- The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: a two-step, two-sample Mendelian randomisation study.Diabetologia · 2017Article
- Aging and adipose tissue: potential interventions for diabetes and regenerative medicine.Experimental gerontology · 2016Review
- Cardiovascular Risk Factors in Gastric Cancer Patients Decrease 1 Year After Gastrectomy.Obesity surgery · 2016Article
- The impact of bariatric surgery on inflammation: quenching the fire of obesity?Current opinion in endocrinology, diabetes, and obesity · 2016Review
- What Can We Learn from Interventions That Change Fat Distribution?Current obesity reports · 2016Review
- Treatment of Obesity: Weight Loss and Bariatric Surgery.Circulation research · 2016Review
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the additional effect of sudden visceral fat reduction by omentectomy on metabolic syndrome, acute-phase reactants, and inflammatory mediators in patients with grade III obesity (G-III O) undergoing laparoscopic Roux-en-Y gastric bypass (LRYGB). RESEARCH DESIGN AND
methodsTwenty-two patients were randomized into two groups, LRYGB alone or with omentectomy. Levels of interleukin-6, C-reactive protein, tumor necrosis factor-alpha, leptin, adiponectin, glucose, total cholesterol, HDL cholesterol, LDL cholesterol, and triglycerides, as well as clinical characteristics, were evaluated before surgery and at 1, 3, 6, and 12 months after surgery. Results were compared between groups.
resultsBaseline characteristics were comparable in both groups. Mean operative time was significantly higher in the group of patients who underwent omentectomy (P < 0.001). Median weight of the omentum was 795 +/- 341 g. In one patient, a duodenal perforation occurred at the time of omentectomy. BMI, blood pressure, glucose, total cholesterol, LDL, and triglycerides significantly improved in both groups at 1, 3, 6, and 12 months of follow-up when compared with basal values. However, there were no consistent statistically significant differences among the groups in terms of metabolic syndrome components, acute-phase reactants, and inflammatory mediators.
conclusionsOmentectomy does not have an ancillary short-term significant impact on the components of metabolic syndrome and does not induce important changes in the inflammatory mediators in patients undergoing LRYGB. Operative time is more prolonged when omentectomy is performed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.