Evidence map›Paper›PMID 20587512›Full record

ArticleGenome research2010

The initial peopling of the Americas: a growing number of founding mitochondrial genomes from Beringia.

Ugo A Perego, Norman Angerhofer, Maria Pala, Anna Olivieri, Hovirag Lancioni, Baharak Hooshiar Kashani, Valeria Carossa, Jayne E Ekins, Alberto Gómez-Carballa, Gabriela Huber and 11 more

Abstract read
In one paragraph

Article in Genome research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed.

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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Ugo A PeregoSorenson Molecular Genealogy Foundation, Salt Lake City, Utah 84115, USA.
Norman Angerhofer
Maria Pala
Anna Olivieri
Hovirag Lancioni
Baharak Hooshiar Kashani
Valeria Carossa
Jayne E Ekins
Alberto Gómez-Carballa
Gabriela Huber
Bettina Zimmermann
Daniel Corach
Nora Babudri
Fausto Panara
Natalie M Myres
Walther Parson
Ornella Semino
Antonio Salas
Scott R Woodward
Alessandro Achilli
Antonio Torroni

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pan-American mitochondrial DNA (mtDNA) haplogroup C1 has been recently subdivided into three branches, two of which (C1b and C1c) are characterized by ages and geographical distributions that are indicative of an early arrival from Beringia with Paleo-Indians. In contrast, the estimated ages of C1d--the third subset of C1--looked too young to fit the above scenario. To define the origin of this enigmatic C1 branch, we completely sequenced 63 C1d mitochondrial genomes from a wide range of geographically diverse, mixed, and indigenous American populations. The revised phylogeny not only brings the age of C1d within the range of that of its two sister clades, but reveals that there were two C1d founder genomes for Paleo-Indians. Thus, the recognized maternal founding lineages of Native Americans are at least 15, indicating that the overall number of Beringian or Asian founder mitochondrial genomes will probably increase extensively when all Native American haplogroups reach the same level of phylogenetic and genomic resolution as obtained here for C1d.

Indexed as

AmericasDNA, MitochondrialEmigration and ImmigrationGenetic VariationGenome, HumanGenome, MitochondrialGeographyHaplotypesHumansIndians, North AmericanMolecular Sequence DataPhylogenyDNA, Mitochondrial

Identifiers

PMID20587512
PMCPMC2928495

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.