ArticleCritical care (London, England)2010
The complex interplay between delirium, sepsis and sedation.
Article in Critical care (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- Socio-Ecologic Perspective: Barriers Complicating Post-Intensive Care Syndrome Mitigation.Journal of patient experience · 2022Article
- Cerebral Autoregulation-Guided Optimal Blood Pressure in Sepsis-Associated Encephalopathy: A Case Series.Journal of intensive care medicine · 2020Article
- What is a Clinician to Do?Critical care medicine · 2018Article
- Comparison of clinical practice guidelines for the management of pain, agitation, and delirium in critically ill adult patients.Acute medicine & surgery · 2018Review
- Preventive Intervention to Prevent Delirium in Patients Hospitalized in Intensive Care Unit.Iranian journal of psychiatry · 2018Review
- [The old man and the I sea U : Essay on faith, fate and evidence - after the manner of Hemingway].Der Anaesthesist · 2017Article
- Impact of non-pharmacological interventions on prevention and treatment of delirium in critically ill patients: protocol for a systematic review of quantitative and qualitative research.Systematic reviews · 2016Article
- A clinical perspective of sepsis-associated delirium.Journal of intensive care · 2016Review
- Should dexmedetomidine replace benzodiazepines as the preferred sedative, as suggested by new guidelines from the society for critical care medicine?The Canadian journal of hospital pharmacy · 2013Article
- The pain, agitation, and delirium practice guidelines for adult critically ill patients: a post-publication perspective.Annals of intensive care · 2013Article
- Delirium epidemiology in critical care (DECCA): an international study.Critical care (London, England) · 2010Article
Corrections and comments
- Comment on
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Critically ill patients requiring mechanical ventilation frequently suffer from intensive care unit delirium, a syndrome associated with numerous poor measured outcomes. The relationship between delirium, sepsis, and sedation is complex. A discussion of the recent study ('Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS [maximizing efficacy of targeted sedation and reducing neurological dysfunction] randomized controlled trial') by Pandharipande and colleagues is presented in this commentary.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.