ReviewGenome biology2010
A hitchhiker's guide to the MADS world of plants.
Review in Genome biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 187 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
187 citing papers in PubMed, 2 syntheses or guidelines pooled it, 383 citations in OpenAlex.
- Combination of meta-analysis of QTL and GWAS to uncover the genetic architecture of seed yield and seed yield components in common bean.The plant genome · 2023Pooled it
- AGL15 Promotion of Somatic Embryogenesis: Role and Molecular Mechanism.Frontiers in plant science · 2022Pooled it
- Mechanisms of Phenotypic Evolution from Molecules to Organisms: Integrating Evolutionary Biochemistry and Evolutionary Developmental Biology.Annual review of ecology, evolution, and systematics · 2026Article
- Characterization of disomic alien addition lines from an intersubgeneric cross between Glycine max and G. tomentella and phenotypic variation within those lines and their progenies.Plant molecular biology · 2026Article
- Genome-wide characterization of MADS-box genes and their roles in axillary bud development in tobacco.Plant cell reports · 2026Article
- Article
- Dynamic evolution of FLC/MAF-like genes accompanying Brassicaceae radiation.Annals of botany · 2026Article
- Cunninghamia lanceolata genome illuminates the evolutionary dynamics of gymnosperms.Cell reports · 2026Article
- ZmEMF1a is required for the maintenance of H2Aub and H3K27me3 modifications in maize kernel development.Genome biology · 2026Article
- 800 million years of co-evolution in the green plant lineage: the case of LEUNIG and SEUSS transcriptional co-regulators.Molecular biology and evolution · 2026Article
- Transcriptomic dissection of floral identity and trichome-derived metabolite pathways in Cannabis sativa L.Planta · 2026Article
- Genome-wide characterization of MADS-box genes reveals CsaSOC1 as a key regulator of flowering in Cannabis sativa L.Plant cell reports · 2026Article
- Genome-wide identification of long non-coding RNAs revealing their regulatory roles under seed development in ricebean (Vigna umbellata).BMC plant biology · 2026Article
- Functional Analysis of MADS-Box Gene Family in Stress Response and Prospects of Breeding Application.Plants (Basel, Switzerland) · 2026Review
- Transcriptional Regulation of Starch Biosynthesis in Sorghum Grain by a MIKC-Type MADS-Box Transcription Factor: An In Vitro Analysis.Plants (Basel, Switzerland) · 2026Article
- Genome-Wide Analysis of the MADS-Box Gene Family and Expression Pattern Under Abiotic Stresses inInternational journal of molecular sciences · 2026Article
- Identification and Expression Analysis ofPlants (Basel, Switzerland) · 2026Article
- Article
- Phylogenomic profile of exon-intron organization across angiosperms, their relationships with protein domains, and functional implications.Nature communications · 2026Article
- Pangenomic characterization and grain-development expression analysis of the OVATE gene family in sorghum.Frontiers in plant science · 2026Article
127 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant life critically depends on the function of MADS-box genes encoding MADS-domain transcription factors, which are present to a limited extent in nearly all major eukaryotic groups, but constitute a large gene family in land plants. There are two types of MADS-box genes, termed type I and type II, and in plants these groups are distinguished by exon-intron and domain structure, rates of evolution, developmental function and degree of functional redundancy. The type I genes are further subdivided into three groups - M alpha, M beta and M gamma - while the type II genes are subdivided into the MIKCC and MIKC* groups. The functional diversification of MIKCC genes is closely linked to the origin of developmental and morphological novelties in the sporophytic (usually diploid) generation of seed plants, most spectacularly the floral organs and fruits of angiosperms. Functional studies suggest different specializations for the different classes of genes; whereas type I genes may preferentially contribute to female gametophyte, embryo and seed development and MIKC*-group genes to male gametophyte development, the MIKCC-group genes became essential for diverse aspects of sporophyte development. Beyond the usual transcriptional regulation, including feedback and feed-forward loops, various specialized mechanisms have evolved to control the expression of MADS-box genes, such as epigenetic control and regulation by small RNAs. In future, more data from genome projects and reverse genetic studies will allow us to understand the birth, functional diversification and death of members of this dynamic and important family of transcription factors in much more detail.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.