ArticleInfection control and hospital epidemiology2010
Chlorhexidine use in the neonatal intensive care unit: results from a national survey.
Article in Infection control and hospital epidemiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.
- Systematic literature review on surgical site preparation in paediatric surgery.BMC pediatrics · 2022Pooled it
- 2% aqueous vs alcohol-based chlorhexidine for skin antisepsis in VLBW neonates undergoing peripheral venipuncture: a non-inferiority trial.Journal of perinatology : official journal of the California Perinatal Association · 2022Trial
- Aqueous chlorhexidine 1% versus 2% for neonatal skin antisepsis: a randomised non-inferiority trial.Archives of disease in childhood. Fetal and neonatal edition · 2021Trial
- One size does not fit all: why universal decolonization strategies to prevent methicillin-resistant Staphylococcus aureus colonization and infection in adult intensive care units may be inappropriate for neonatal intensive care units.Journal of perinatology : official journal of the California Perinatal Association · 2014Trial
- Methicillin-resistant Staphylococcus aureus colonization: a three-year prospective study in a neonatal intensive care unit in Italy.PloS one · 2014Trial
- The use of 2% chlorhexidine gluconate in 70% isopropyl alcohol for skin disinfection prior to central venous catheterization in infants: a national survey of the Italian Society of Neonatology.Italian journal of pediatrics · 2025Article
- Efficacy and safety of three antiseptics for neonatal skin disinfection: a cohort study.Pediatric research · 2025Article
- Effectiveness and safety of chlorhexidine gluconate double-cleansing for surgical site infection prevention in neonatal intensive care unit surgical patients.Annals of surgical treatment and research · 2024Article
- Microbiome dysbiosis: a modifiable state and target to prevent Staphylococcus aureus infections and other diseases in neonates.Journal of perinatology : official journal of the California Perinatal Association · 2024Review
- Transferring an extremely premature infant to an extra-uterine life support system: a prospective view on the obstetric procedure.Frontiers in pediatrics · 2024Review
- Assessment of Alcohol Exposure From Alcohol-Based Disinfectants Among Premature Infants in Neonatal Incubators in Japan.JAMA network open · 2023Article
- Healthcare-Associated Infection Prevention Interventions for Neonates in Resource-Limited Settings.Frontiers in pediatrics · 2022Review
- Chlorhexidine gluconate usage is associated with antiseptic tolerance in staphylococci from the neonatal intensive care unit.JAC-antimicrobial resistance · 2021Article
- Impact of 1% chlorhexidine gluconate bathing and emollient application on bacterial pathogen colonization dynamics in hospitalized preterm neonates - A pilot clinical trial.EClinicalMedicine · 2021Article
- [Operation and management guidelines for peripherally inserted central catheter in neonates (2021)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- Best Practices of Blood Cultures in Low- and Middle-Income Countries.Frontiers in medicine · 2019Review
- The impact of chlorhexidine gluconate bathing on skin bacterial burden of neonates admitted to the Neonatal Intensive Care Unit.Journal of perinatology : official journal of the California Perinatal Association · 2019Observational
- The downside of antimicrobial agents for wound healing.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Review
- Trends in Chlorhexidine Use in US Neonatal Intensive Care Units: Results From a Follow-Up National Survey.Infection control and hospital epidemiology · 2016Article
- Antiseptic use in the neonatal intensive care unit - a dilemma in clinical practice: An evidence based review.World journal of clinical pediatrics · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Infection prevention guidelines do not endorse chlorhexidine gluconate (CHG) use in neonates who are less than 2 months old. A survey of US neonatology program directors revealed that most neonatal intensive care units use CHG, often with some restrictions. Prospective studies are needed to further address concerns regarding the safety of CHG in patients in the neonatal intensive care unit.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.