ArticleDose-response : a publication of International Hormesis Society2009
The dose window for radiation-induced protective adaptive responses.
Article in Dose-response : a publication of International Hormesis Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Bacterial Adaptation to Radiofrequency Electromagnetic Fields Based on Experiences from Ionizing Radiation.Journal of biomedical physics & engineering · 2026Review
- Indoor radon concentration and risk and severity of inflammatory bowel diseases: a case-control study.Therapeutic advances in gastroenterology · 2025Article
- Low-Dose Ionizing Radiation Exposure on Human Male Gametes: Damage or Benefit.Life (Basel, Switzerland) · 2024Review
- The radiation adaptive response and priming dose influence: the quantification of the Raper-Yonezawa effect and its three-parameter model for postradiation DNA lesions and mutations.Radiation and environmental biophysics · 2022Article
- Hospitalizations Among Chernobyl-Exposed Immigrants to the Negev of Israel, 1992-2017: A Historical Follow-Up Study.Journal of immigrant and minority health · 2022Article
- Different responses of normal cells (red blood cells) and cancer cells (K562 and K562/Dox cells) to low-doseMolecular and clinical oncology · 2021Article
- Degradation of nuclear and mitochondrial DNA after γ-irradiation and its effect on forensic genotyping.Forensic science, medicine, and pathology · 2020Article
- Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations.Nucleic acids research · 2016Article
- Klebsiella pneumonia, a Microorganism that Approves the Non-linear Responses to Antibiotics and Window Theory after Exposure to Wi-Fi 2.4 GHz Electromagnetic Radiofrequency Radiation.Journal of biomedical physics & engineering · 2015Article
- Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation.Journal of visualized experiments : JoVE · 2015Article
- Optimal conditions of LDR to protect the kidney from diabetes: exposure to 12.5 mGy X-rays for 8 weeks efficiently protects the kidney from diabetes.Life sciences · 2014Article
- Non-linear adaptive phenomena which decrease the risk of infection after pre-exposure to radiofrequency radiation.Dose-response : a publication of International Hormesis Society · 2014Article
- Low-dose radiation exposure induces a HIF-1-mediated adaptive and protective metabolic response.Cell death and differentiation · 2014Article
- Window theory in non-ionizing radiation-induced adaptive responses.Dose-response : a publication of International Hormesis Society · 2013Article
- Potential treatment of inflammatory and proliferative diseases by ultra-low doses of ionizing radiations.Dose-response : a publication of International Hormesis Society · 2012Article
- Protective Effect of γ-Irradiation Against Hypochlorous Acid-Induced Haemolysis in Human Erythrocytes.Dose-response : a publication of International Hormesis Society · 2012Article
- Identification of proteins secreted into the medium by human lymphocytes irradiated in vitro with or without adaptive environments.Health physics · 2012Article
- Radiation hormesis: historical perspective and implications for low-dose cancer risk assessment.Dose-response : a publication of International Hormesis Society · 2010Article
- Special issue introduction.Dose-response : a publication of International Hormesis Society · 2010Article
- Biophysical Modeling of the Ionizing Radiation Influence on Cells Using the Stochastic (Monte Carlo) and Deterministic (Analytical) Approaches.Dose-response : a publication of International Hormesis SocietyReview
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Authors and funding
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Abstract
Adaptive responses to low doses of low LET radiation occur in all organisms thus far examined, from single cell lower eukaryotes to mammals. These responses reduce the deleterious consequences of DNA damaging events, including radiation-induced or spontaneous cancer and non-cancer diseases in mice. The adaptive response in mammalian cells and mammals operates within a certain window that can be defined by upper and lower dose thresholds, typically between about 1 and 100 mGy for a single low dose rate exposure. However, these thresholds for protection are not a fixed function of total dose, but also vary with dose rate, additional radiation or non-radiation stressors, tissue type and p53 functional status. Exposures above the upper threshold are generally detrimental, while exposures below the lower threshold may or may not increase either cancer or non-cancer disease risk.
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