Evidence map›Paper›PMID 20585329›Full record

ReviewNature reviews. Cardiology2010

Four decades of Fontan palliation.

Marc R de Leval, John E Deanfield

Registry-linked trialAbstract readHistorical ArticleReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02414321 (The Role of the Pulmonary Vasculature in the Fontan Circulation), which is not on this map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02414321 unknown statusnot on this mapstarted 2015, after this paper: background citation

The Role of the Pulmonary Vasculature in the Fontan Circulation

TypeobservationalSponsorUniversity Medical Center GroningenRan2015 to 2024Enrolled20ConditionsCongenital Heart Disease, Fontan Operation, Pulmonary Vascular Resistance, Pulmonary Vascular Remodeling
3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Heart failure in a patient with Glenn circulation during secondary pregnancy with a single ventricle: A rare case report.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Endothelial dysfunction in single ventricle physiology and the Fontan circulation - What lies ahead.International journal of cardiology. Congenital heart disease · 2025
    Review
  6. Article
  7. How cardiac output is controlled in a Fontan circulation: an update.Interdisciplinary cardiovascular and thoracic surgery · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. The Secrets of the Frogs Heart.Pediatric cardiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marc R de LevalCardiothoracic Unit, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, UK.
John E Deanfield

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Fontan palliation was introduced in 1968 to treat cardiac malformations unsuitable for biventricular repair. This procedure has transformed the surgical management of congenital heart disease. In this Review, we reflect on the outcomes and clinical problems associated with this unique circulation after more than 40 years of experience. We also summarize the evolution of the Fontan procedure, highlight the long-term clinical issues and their management, and consider future expectations of a circulation driven by a single ventricle with the systemic and pulmonary blood flow in series rather than in parallel.

Indexed as

Arrhythmias, CardiacExercise ToleranceFontan ProcedureHeart Bypass, RightHeart Defects, CongenitalHeart FailureHistory, 20th CenturyHistory, 21st CenturyHumansLiver DiseasesPulmonary CirculationTreatment Outcome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.