Evidence map›Paper›PMID 20584543›Full record

Trial reportThe Journal of allergy and clinical immunology2010

Maternal dietary pattern during pregnancy is not associated with recurrent wheeze in children.

Nancy E Lange, Sheryl L Rifas-Shiman, Carlos A Camargo, Diane R Gold, Matthew W Gillman, Augusto A Litonjua

Open access · greenAbstract readClinical TrialComparative Study
In one paragraph

Trial report in The Journal of allergy and clinical immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 6 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 6 syntheses or guidelines pooled it, 103 citations in OpenAlex.

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  4. Dietary factors during pregnancy and atopic outcomes in childhood: A systematic review from the European Academy of Allergy and Clinical Immunology.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Nancy E LangeChanning Laboratory, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. nlange@partners.org
Sheryl L Rifas-Shiman
Carlos A Camargo
Diane R Gold
Matthew W Gillman
Augusto A Litonjua
Harvard University · USBrigham and Women's Hospital · USHarvard Pilgrim Health Care · USMassachusetts General Hospital · US

Funding

Prenatal environmental determinants of health in young adulthood: a lifecourse approachR01HD034568 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI Marie-France Hivert, Emily Oken · 1998 to 2026
$20.6M
SYSTEMS APPROACHES TO THE EPIDEMIOLOGY, GENETICS AND GENOMICS OF LUNG DISEASEST32HL007427 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI DAWN L DEMEO, Edwin K Silverman · 1985 to 2026
$13.6M
The Epidemiology of Home Allergens and AsthmaR01AI035786 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLD, DIANE R · 1994 to 2010
$9.5M
NUTRITION IN PREGNANCY, BIRTH WEIGHT, &CHILDHOOD ASTHMAR01HL064925 · NHLBI · HARVARD PILGRIM HEALTH CARE, INC. · PI GILLMAN, MATTHEW W · 2000 to 2010
$7.5M
Pre- and Peri-natal Predictors of Childhood ObesityR37HD034568 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI GILLMAN, MATTHEW W · 2012 to 2015
$4.5M
Patient-oriented research in early life origins of CVDK24HL068041 · NHLBI · HARVARD PILGRIM HEALTH CARE, INC. · PI GILLMAN, MATTHEW W · 2001 to 2010
$1.4M
DIET, IMMUNE MODULATION, AND ASTHMA IN EARLY LIFER01HL061907 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 1998 to 2002
$647k
The Epidemiology of Home Allergens and AsthmaR56AI035786 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLD, DIANE R · 2011 to 2011
$486k
NHLBI NIH HHS HL007427NHLBI NIH HHS HL61907NHLBI NIH HHS HL64925NHLBI NIH HHS HL68041NHLBI NIH HHS K24 HL068041NHLBI NIH HHS R01 HL064925NHLBI NIH HHS T32 HL007427NIAID NIH HHS AI35786NIAID NIH HHS R01 AI035786NIAID NIH HHS R56 AI035786NICHD NIH HHS HD34568NICHD NIH HHS R01 HD034568NICHD NIH HHS R37 HD034568
6 · The paper itself

Abstract

backgroundThe rise in asthma prevalence over the last few decades may be a result of changes in prenatal or early-life environment, including maternal diet during pregnancy. Previous studies have found associations between individual foods or nutrients consumed during pregnancy and asthma or wheeze in children, but these may be confounded by overall dietary pattern.

objectiveTo determine whether overall maternal dietary pattern during pregnancy is associated with recurrent wheeze in children.

methodsA total of 1376 mother-infant pairs from Project Viva, a longitudinal prebirth cohort, who had responses for food frequency questionnaires in the first and second trimester and outcome data at 3 years of age were included. Multivariable logistic regression was used to look at associations between dietary pattern and the primary outcome of recurrent wheeze at 3 years. Overall dietary pattern was examined by using Mediterranean diet score, Alternate Healthy Eating Index modified for pregnancy (AHEI-P), and principal components analysis to look at Western and Prudent diets.

resultsNone of these dietary patterns was associated with the primary outcome of recurrent wheeze in children in either the crude or the multivariable model (multivariable model, odds ratio per 1-point increase in Mediterranean diet, 0.98 [95% CI, 0.89-1.08]; AHEI-P, 1.07 [0.87-1.30]; Prudent, 1.02 [0.83-1.26]; Western, 0.98 [0.81-1.19]).

conclusionOverall dietary pattern during pregnancy is not associated with recurrent wheeze in this cohort. Maternal intake of individual nutrients may be more important determinants of offspring wheeze-associated illness than is dietary pattern.

Indexed as

Feeding BehaviorPrenatal Exposure Delayed EffectsAdultAsthmaChild, PreschoolCohort StudiesFemaleHumansInfantMaleModels, TheoreticalPregnancyPrevalenceRespiratory Sounds

Identifiers

PMID20584543
PMCPMC2917539
OpenAlexW2067474259

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.