ArticleThe Journal of clinical psychiatry2010
Are maternal depression or symptom severity associated with breastfeeding intention or outcomes?
Article in The Journal of clinical psychiatry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A mixed methods systematic review exploring infant feeding experiences and support in women with severe mental illness.Maternal & child nutrition · 2023Pooled it
- Perinatal depressive symptoms and breastfeeding behaviors: A systematic literature review and biosocial research agenda.Journal of affective disorders · 2021Pooled it
- The association between psychological factors and breastfeeding behaviour in women with a body mass index (BMI) ≥30 kg mObesity reviews : an official journal of the International Association for the Study of Obesity · 2018Pooled it
- Increased breastfeeding rates in black women after a treatment intervention.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2013Trial
- Antidepressants and breastfeeding behaviors: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- Perinatal depression and breastfeeding: a longitudinal investigation of the bidirectional relationship in Pakistan.Archives of women's mental health · 2026Article
- A Population-Based Cohort Study of Early Infant Feeding Initiation in Maternal Bipolar Disorder.Bipolar disorders · 2025Article
- Psychological factors affecting breastfeeding during the perinatal period in the UK: an observational longitudinal study.BMC public health · 2025Observational
- Trends in the prevalence of antenatal and postnatal depression in Bangladesh: A systematic review and meta-analysis.Heliyon · 2025Article
- Breastfeeding Intention, Knowledge, and Attitude of Pregnant Women in Treatment for Opioid Use Disorder.American journal of perinatology · 2024Article
- Association between breastfeeding cessation among under six-month-old infants and postpartum depressive symptoms in Nevada.PloS one · 2024Article
- The most common medications dispensed to lactating persons: An electronic health record-based approach.Pharmacoepidemiology and drug safety · 2023Article
- The Relationship between Psychological Suffering, Value of Maternal Cortisol during Third Trimester of Pregnancy and Breastfeeding Initiation.Medicina (Kaunas, Lithuania) · 2023Article
- Perinatal antidepressant use and breastfeeding outcomes: Findings from the Norwegian Mother, Father and Child Cohort Study.Acta obstetricia et gynecologica Scandinavica · 2022Article
- Prenatal Depression, Breastfeeding, and Infant Gut Microbiota.Frontiers in microbiology · 2021Article
- Pharmacotherapy for depression and bipolar disorder during lactation: A framework to aid decision making.Seminars in perinatology · 2020Review
- A prospective study of maternal postnatal depressive symptoms with infant-feeding practices in a Chinese birth cohort.BMC pregnancy and childbirth · 2019Article
- The Mood, Mother, and Infant Study: Associations Between Maternal Mood in Pregnancy and Breastfeeding Outcome.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2019Article
- Article
- Impact of serotonin reuptake inhibitor use on breast milk supply in mothers of preterm infants: a retrospective cohort study.British journal of clinical pharmacology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveBreastfeeding confers many health benefits to mothers and infants, while depression negatively affects mothers and infants. The aims of this study were to determine relationships between (1) major depressive disorder (MDD) and depressive symptom severity during pregnancy and breastfeeding intention; (2) MDD and depressive symptom severity during pregnancy and breastfeeding initiation and status at 2 and 12 weeks; and (3) serotonin reuptake inhibitor (SRI) use and breastfeeding intention, initiation, and status at 2 and 12 weeks.
methodWomen were followed prospectively from pregnancy through 12 weeks postpartum for infant feeding intention (breast, breast and formula, formula, and uncertain), feeding practices and MDD (Structured Clinical Interview for DSM-IV Disorders), and depressive symptom severity (Hamilton Depression Rating Scale). Bivariate analyses and multivariable regression modeling were conducted. The study was conducted from July 2004 to September 2007.
resultsStudy participants (intention n = 168, initiation n = 151, 2 weeks n = 137, 12 weeks n=103) were well educated (63% college degrees), older (49% ≥ or = 31 years), and predominantly white (77%). At enrollment, 23% had MDD, 21% had significant depressive symptoms, and 16% were taking an SRI. Neither MDD nor depressive symptom severity in pregnancy was related to breastfeeding intention, initiation or duration at 2 and 12 weeks. Intention to exclusively breastfeed was the most significant predictor of breastfeeding initiation and duration. SRI use in pregnancy was negatively associated with breastfeeding intention. SRI use at 2 weeks was negatively associated with 12-week breastfeeding status.
conclusionPregnancy is the optimal time to intervene to increase breastfeeding rates. Future research should identify strategies to overcome breastfeeding barriers posed by SRI use.
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