ReviewBreast cancer research : BCR2010
The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis.
Review in Breast cancer research : BCR, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- The Genomic Profile of Pregnancy-Associated Breast Cancer: A Systematic Review.Frontiers in oncology · 2020Pooled it
- Unraveling the role of stromal disruption in aggressive breast cancer etiology and outcomes.Journal of the National Cancer Institute · 2025Article
- Contribution of Prediagnostic Host Factors to Shaping the Stromal Microenvironment of Breast Cancer among Sub-Saharan African Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- The relation between excess adiposity and breast cancer in women: Clinical implications and management.Critical reviews in oncology/hematology · 2024Review
- The mutational landscape of the adult healthy parous and nulliparous human breast.Nature communications · 2023Article
- Host, reproductive, and lifestyle factors in relation to quantitative histologic metrics of the normal breast.Breast cancer research : BCR · 2023Article
- Effects of Hormones on Breast Development and Breast Cancer Risk in Transgender Women.Cancers · 2022Review
- The Mammary Gland: Basic Structure and Molecular Signaling during Development.International journal of molecular sciences · 2022Review
- Deep Learning Image Analysis of Benign Breast Disease to Identify Subsequent Risk of Breast Cancer.JNCI cancer spectrum · 2021Article
- The Importance of Breast Adipose Tissue in Breast Cancer.International journal of molecular sciences · 2020Review
- Age-correlated protein and transcript expression in breast cancer and normal breast tissues is dominated by host endocrine effects.Nature cancer · 2020Article
- Associations of reproductive factors with breast cancer prognosis and the modifying effects of menopausal status.Cancer medicine · 2020Observational
- Hyaline fibrous involution of breast lobules: a histologic finding associated with germline BRCA mutation.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2019Article
- Studies of postpartum mammary gland involution reveal novel pro-metastatic mechanisms.Journal of cancer metastasis and treatment · 2019Article
- Obesity-Activated Adipose-Derived Stromal Cells Promote Breast Cancer Growth and Invasion.Neoplasia (New York, N.Y.) · 2018Article
- Article
- The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy.Endocrine-related cancer · 2017Review
- Association of Parity and Time since Last Birth with Breast Cancer Prognosis by Intrinsic Subtype.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016Article
- Methods of Cell Propulsion through the Local Stroma in Breast Cancer.International journal of breast cancer · 2014Review
- Genomic signatures of pregnancy-associated breast cancer epithelia and stroma and their regulation by estrogens and progesterone.Hormones & cancer · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Breast cancer is a heterogeneous disease whose prognosis varies depending upon the developmental stage of the breast tissue at diagnosis. Notably, breast cancers associated with pregnancy exhibit increased rates of metastasis and poorer long-term survival compared to those diagnosed after menopause. However, postmenopausal breast cancers associated with obesity exhibit a more aggressive behavior and confer decreased overall patient survival compared to those diagnosed in non-obese individuals. Since the mammary gland is a dynamic tissue that undergoes significant changes throughout a woman's lifetime, especially during pregnancy and following menopause, we present evidence to support the notion that changes occurring throughout development within the mammary stromal compartment may account for some of the biological differences in breast cancer subtypes and behaviors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.