Evidence map›Paper›PMID 20584328›Full record

ArticleGenome biology2010

Estimating enrichment of repetitive elements from high-throughput sequence data.

Daniel S Day, Lovelace J Luquette, Peter J Park, Peter V Kharchenko

Open access · goldAbstract read
In one paragraph

Article in Genome biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 115 citations in OpenAlex.

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  9. CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection.Proceedings of the National Academy of Sciences of the United States of America · 2022
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Daniel S DayHarvard-MIT Health Sciences and Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
Lovelace J Luquette
Peter J Park
Peter V Kharchenko
Harvard University · USBoston Children's Hospital · USHarvard–MIT Division of Health Sciences and Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe computational methods for analysis of repetitive elements from short-read sequencing data, and apply them to study histone modifications associated with the repetitive elements in human and mouse cells. Our results demonstrate that while accurate enrichment estimates can be obtained for individual repeat types and small sets of repeat instances, there are distinct combinatorial patterns of chromatin marks associated with major annotated repeat families, including H3K27me3/H3K9me3 differences among the endogenous retroviral element classes.

Indexed as

Databases, Nucleic AcidAnimalsBase SequenceCD4-Positive T-LymphocytesCell LineEmbryo, MammalianFibroblastsHigh-Throughput Screening AssaysHistonesHumansMicePhylogenyProtein Processing, Post-TranslationalRepetitive Sequences, Nucleic AcidSequence Analysis, DNAHistones

Identifiers

PMID20584328
PMCPMC2911117
OpenAlexW2136575984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.