Evidence map›Paper›PMID 20584284›Full record

ReviewRespiratory research2010

Clinical use of biomarkers of survival in pulmonary fibrosis.

Michiel Thomeer, Jan C Grutters, Wim A Wuyts, Stijn Willems, Maurits G Demedts

Open access · goldAbstract readReview
In one paragraph

Review in Respiratory research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Prognostic value of [Scientific reports · 2025
    Article
  3. Article
  4. Pulmonary long-term consequences of COVID-19 infections after hospital discharge.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2021
    Article
  5. Article
  6. Article
  7. A novel genomic signature with translational significance for human idiopathic pulmonary fibrosis.American journal of respiratory cell and molecular biology · 2015
    Article
  8. Article
  9. Idiopathic pulmonary fibrosis: the need for early diagnosis.Multidisciplinary respiratory medicine · 2013
    Article
  10. Article
  11. Idiopathic pulmonary fibrosis: current challenges and future perspectives.European respiratory review : an official journal of the European Respiratory Society · 2013
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Michiel ThomeerDepartment of Respiratory Medicine, Ziekenhuis Oost-Limburg, Genk, Belgium. michiel@thomeer.org
Jan C Grutters
Wim A Wuyts
Stijn Willems
Maurits G Demedts
KU Leuven · BESt. Antonius Ziekenhuis · NLUniversitair Ziekenhuis Leuven · BEZiekenhuis Oost-Limburg · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBiologic predictors or biomarkers of survival in pulmonary fibrosis with a worse prognosis, more specifically in idiopathic pulmonary fibrosis would help the clinician in deciding whether or not to treat since treatment carries a potential risk for adverse events. These decisions are made easier if accurate and objective measurements of the patients' clinical status can predict the risk of progression to death.

methodA literature review is given on different biomarkers of survival in interstitial lung disease, mainly in IPF, since this disease has the worst prognosis.

conclusionSerum biomarkers, and markers measured by medical imaging as HRCT, pertechnegas, DTPA en FDG-PET are not ready for clinical use to predict mortality in different forms of ILD. A baseline FVC, a change of FVC of more than 10%, and change in 6MWD are clinically helpful predictors of survival.

Indexed as

BiomarkersDiagnostic ImagingExercise TestHumansPredictive Value of TestsPrognosisPulmonary FibrosisRespiratory Function TestsRisk AssessmentRisk FactorsSurvival AnalysisTime FactorsBiomarkers

Identifiers

PMID20584284
PMCPMC2907324
OpenAlexW2139413207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.