Trial reportWorld journal of surgery2010
Routine ultrasound and limited computed tomography for the diagnosis of acute appendicitis.
Trial report in World journal of surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 135 citations in OpenAlex.
- Computed tomography for diagnosis of acute appendicitis in adults.The Cochrane database of systematic reviews · 2019Pooled it
- Pooled it
- Negative Appendectomy Rates and Their Correlation With the Use of Histopathology: A Clinical Audit.Cureus · 2026Article
- Current usage and diagnostic performance of cross-sectional imaging in patients with suspected acute appendicitis: a national survey in China.Abdominal radiology (New York) · 2025Article
- Combined clinical accuracy of inflammatory markers and ultrasound for the diagnosis of acute appendicitis.Ultrasound (Leeds, England) · 2023Article
- Accuracy of emergency physician bedside ultrasonography compared with private teleradiologist for acute appendicitis diagnosis.Irish journal of medical science · 2023Article
- Routine Computed Tomography Versus Selective Imaging: An Audit of Negative Appendicectomy Rates in Two Hospitals.Cureus · 2022Article
- Article
- Value of Alvarado scoring system in diagnosis of acute appendicitis.Annals of medicine and surgery (2012) · 2022Article
- Low-Dose Abdominal CT for Evaluating Suspected Appendicitis in Adolescents and Young Adults: Review of Evidence.Korean journal of radiology · 2022Review
- The Dynamics of Inflammatory Markers in Patients with Suspected Acute Appendicitis.Medicina (Kaunas, Lithuania) · 2021Article
- Article
- DIALAPP: a prospective validation of a new diagnostic algorithm for acute appendicitis.Langenbeck's archives of surgery · 2021Article
- Predictors risk factors for acute complex appendicitis pain in patients: Are there gender differences?Journal of family medicine and primary care · 2020Article
- Aeromedical retrieval for suspected appendicitis in rural and remote paediatric patients.Australasian journal of ultrasound in medicine · 2020Article
- Secondary imaging for suspected appendicitis after equivocal ultrasound: time to disposition of MRI compared to CT.Emergency radiology · 2018Article
- Efficacy of the Evaluation of Inflammatory Markers for the Reduction of Negative Appendectomy Rates.The Indian journal of surgery · 2018Article
- Acute Appendicitis in the Early Stage after Orthotopic Liver Transplantation.Chinese medical journal · 2017Article
- Comment on article entitled "The RIPASA score is sensitive and specific for the diagnosis of acute appendicitis in a western population".International journal of colorectal disease · 2017Article
- The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections.World journal of emergency surgery : WJES · 2017Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute appendicitis continues to be a challenging diagnosis. Preoperative radiological imaging using ultrasound (US) or computed tomography (CT) has gained popularity as it may offer a more accurate diagnosis than classic clinical evaluation. The optimal implementation of these diagnostic modalities has yet to be established. The aim of the present study was to investigate a diagnostic pathway that uses routine US, limited CT, and clinical re-evaluation for patients with acute appendicitis.
methodsA prospective analysis was performed of all patients presenting with acute abdominal pain at the emergency department from June 2005 until July 2006 using a structured diagnosis and management flowchart. Daily practice was mimicked, while ensuring a valid assessment of clinical and radiological diagnostic accuracies and the effect they had on patient management.
resultsA total of 802 patients were included in this analysis. Additional radiological imaging was performed in 96.3% of patients with suspected appendicitis (n = 164). Use of CT was kept to a minimum (17.9%), with a US:CT ratio of approximately 6:1. Positive and negative predictive values for the clinical diagnosis of appendicitis were 63 and 98%, respectively; for US 94 and 97%, respectively; and for CT 100 and 100%, respectively. The negative appendicitis rate was 3.3%, the perforation rate was 23.5%, and the missed perforated appendicitis rate was 3.4%. No (diagnostic) laparoscopies were performed.
conclusionsA diagnostic pathway using routine US, limited CT, and clinical re-evaluation for patients with acute abdominal pain can provide excellent results for the diagnosis and treatment of appendicitis.
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