ReviewCellular and molecular life sciences : CMLS2010
Rab protein evolution and the history of the eukaryotic endomembrane system.
Review in Cellular and molecular life sciences : CMLS, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
52 citing papers in PubMed, 93 citations in OpenAlex.
- Article
- Insights on the intracellular trafficking of calcifying medium in a reef-building coral.Communications biology · 2025Article
- Structural basis for Rab6 activation by the Ric1-Rgp1 complex.Nature communications · 2024Article
- Structural basis for Rab6 activation by the Ric1-Rgp1 complex.bioRxiv : the preprint server for biology · 2024Article
- Article
- Autophagy and neurodegeneration: Unraveling the role of C9ORF72 in the regulation of autophagy and its relationship to ALS-FTD pathology.Frontiers in cellular neuroscience · 2023Review
- Genome-Wide Analysis of theInternational journal of molecular sciences · 2022Article
- How "Neuronal" Are Human Skin Mast Cells?International journal of molecular sciences · 2022Review
- Interactome and evolutionary conservation of Dictyostelid small GTPases and their direct regulators.Small GTPases · 2022Article
- Phylogenetic reconstruction and evolution of the Rab GTPase gene family in Amoebozoa.Small GTPases · 2022Article
- Role ofPlant direct · 2020Article
- A Review of Diatom Lipid Droplets.Biology · 2020Review
- The evolutionary landscape of the Rab family in chordates.Cellular and molecular life sciences : CMLS · 2019Article
- Comparative in depth RNA sequencing of P. tricornutum's morphotypes reveals specific features of the oval morphotype.Scientific reports · 2018Article
- Regulation of early endosomes across eukaryotes: Evolution and functional homology of Vps9 proteins.Traffic (Copenhagen, Denmark) · 2018Article
- Article
- Rab GTPases and Membrane Trafficking in Neurodegeneration.Current biology : CB · 2018Review
- Phylogenetic Analysis of the vesicular fusion SNARE machinery revealing its functional divergence across Eukaryotes.Bioinformation · 2018Article
- Rab GTPases in Osteoclastic Endomembrane Systems.BioMed research international · 2018Review
- Genome-wide characterization of the Rab gene family in Gossypium by comparative analysis.Botanical studies · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Spectacular increases in the quantity of sequence data genome have facilitated major advances in eukaryotic comparative genomics. By exploiting homology with classical model organisms, this makes possible predictions of pathways and cellular functions currently impossible to address in intractable organisms. Echoing realization that core metabolic processes were established very early following evolution of life on earth, it is now emerging that many eukaryotic cellular features, including the endomembrane system, are ancient and organized around near-universal principles. Rab proteins are key mediators of vesicle transport and specificity, and via the presence of multiple paralogues, alterations in interaction specificity and modification of pathways, contribute greatly to the evolution of complexity of membrane transport. Understanding system-level contributions of Rab proteins to evolutionary history provides insight into the multiple processes sculpting cellular transport pathways and the exciting challenges that we face in delving further into the origins of membrane trafficking specificity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.