Trial reportThe New England journal of medicine2010
A school-based intervention for diabetes risk reduction.
Trial report in The New England journal of medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00458029 (Studies to Treat Or Prevent Pediatric Type 2 Diabetes), which is not on this map. Cited by 165 papers, 28 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Studies to Treat Or Prevent Pediatric Type 2 Diabetes (STOPP-T2D) Middle-School Based Primary Prevention Trial (HEALTHY)
Who cites it
165 citing papers in PubMed, 28 syntheses or guidelines pooled it, 347 citations in OpenAlex.
- How to Teach Healthy Life-Style Efficiently in a Pediatric Outpatient Setting: Proposal of an Innovative Tridimensional Pyramid.Nutrients · 2026Pooled it
- Which school-based interventions work better to combat obesity in children? A network meta-analysis.Systematic reviews · 2025Pooled it
- Impact of multi-component school food environment interventions on adiposity and food consumption in children and adolescents: systematic review and meta-analysis.Cadernos de saude publica · 2025Pooled it
- Strategies for enhancing the implementation of school-based policies or practices targeting diet, physical activity, obesity, tobacco or alcohol use.The Cochrane database of systematic reviews · 2024Pooled it
- Waist circumference as a parameter in school-based interventions to prevent overweight and obesity - a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Interventions to prevent obesity in children aged 5 to 11 years old.The Cochrane database of systematic reviews · 2024Pooled it
- Comparative effectiveness of school-based obesity prevention programs for children and adolescents: a systematic review and network meta-analysis.Frontiers in public health · 2024Pooled it
- Strategies for enhancing the implementation of school-based policies or practices targeting diet, physical activity, obesity, tobacco or alcohol use.The Cochrane database of systematic reviews · 2022Pooled it
- School-based physical activity programs for promoting physical activity and fitness in children and adolescents aged 6 to 18.The Cochrane database of systematic reviews · 2021Pooled it
- A systematic review and meta-analysis of school-based interventions with health education to reduce body mass index in adolescents aged 10 to 19 years.The international journal of behavioral nutrition and physical activity · 2021Pooled it
- The effectiveness of pediatric obesity prevention policies: a comprehensive systematic review and dose-response meta-analysis of controlled clinical trials.Journal of translational medicine · 2020Pooled it
- A systematic review and meta-analysis of the overall effects of school-based obesity prevention interventions and effect differences by intervention components.The international journal of behavioral nutrition and physical activity · 2019Pooled it
- Interventions for preventing obesity in children.The Cochrane database of systematic reviews · 2019Pooled it
- Environmental interventions to reduce the consumption of sugar-sweetened beverages and their effects on health.The Cochrane database of systematic reviews · 2019Pooled it
- Effectiveness of school food environment policies on children's dietary behaviors: A systematic review and meta-analysis.PloS one · 2018Pooled it
- Healthy food procurement and nutrition standards in public facilities: evidence synthesis and consensus policy recommendations.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2018Pooled it
- Strategies for enhancing the implementation of school-based policies or practices targeting risk factors for chronic disease.The Cochrane database of systematic reviews · 2017Pooled it
- Prevention of Type 2 Diabetes in U.S. Hispanic Youth: A Systematic Review of Lifestyle Interventions.American journal of preventive medicine · 2017Pooled it
- Pediatric Obesity-Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline.The Journal of clinical endocrinology and metabolism · 2017 · on this mapGuideline
- Pooled it
105 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundWe examined the effects of a multicomponent, school-based program addressing risk factors for diabetes among children whose race or ethnic group and socioeconomic status placed them at high risk for obesity and type 2 diabetes.
methodsUsing a cluster design, we randomly assigned 42 schools to either a multicomponent school-based intervention (21 schools) or assessment only (control, 21 schools). A total of 4603 students participated (mean [+/- SD] age, 11.3 [+/- 0.6 years; 54.2% Hispanic and 18.0% black; 52.7% girls). At the beginning of 6th grade and the end of 8th grade, students underwent measurements of body-mass index (BMI), waist circumference, and fasting glucose and insulin levels.
resultsThere was a decrease in the primary outcome--the combined prevalence of overweight and obesity--in both the intervention and control schools, with no significant difference between the school groups. The intervention schools had greater reductions in the secondary outcomes of BMI z score, percentage of students with waist circumference at or above the 90th percentile, fasting insulin levels (P=0.04 for all comparisons), and prevalence of obesity (P=0.05). Similar findings were observed among students who were at or above the 85th percentile for BMI at baseline. Less than 3% of the students who were screened had an adverse event; the proportions were nearly equivalent in the intervention and control schools.
conclusionsOur comprehensive school-based program did not result in greater decreases in the combined prevalence of overweight and obesity than those that occurred in control schools. However, the intervention did result in significantly greater reductions in various indexes of adiposity. These changes may reduce the risk of childhood-onset type 2 diabetes. (Funded by the National Institutes of Health and the American Diabetes Association; ClinicalTrials.gov number, NCT00458029.)
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.