ReviewMathematical biosciences2010
Lessons from models of pancreatic beta cells for engineering glucose-sensing cells.
Review in Mathematical biosciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Physiologic hormone administration improves HbA1C in Native Americans with type 2 diabetes: A retrospective study and review of insulin secretion and action.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Review
- Pulsatile insulin secretion, impaired glucose tolerance and type 2 diabetes.Molecular aspects of medicine · 2015Review
- Mathematical models of electrical activity of the pancreatic β-cell: a physiological review.Islets · 2014Review
- Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Mathematical models of pancreatic beta cells suggest design principles that can be applied to engineering cells to sense glucose and secrete insulin. Engineering cells can potentially both contribute to future diabetes therapies and generate new insights into beta-cell function. The focus is on ion channels, Ca(2+)handling, and elements of metabolism that combine to produce the varied oscillatory patterns exhibited by beta cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.